Numerous reports document that the 70 kDa heat shock proteins are not only intracellular proteins but are also present in blood and other extracellular compartments. How they affect cell function from the extracellular space remains unclear. Using two well-characterized cell types from the sea urchin, we show that extracellular mixtures of the constitutive and inducible forms of the 70 kDa heat...

The chemical kinetics of n-heptane (n-C 7 H 16 ) – an important reference compound for real fuels – oxidation are well studied at stoichiometric and lean conditions. However, there is only limited information on the n-heptane chemical kinetics in fuel-rich combustion. In order to verify the accuracy of chemical kinetic models at these conditions, the oxidation of rich n-heptane mixtures has bee...

In measuring reaction time (RT) to simultaneously presented stimuli, Todd (1912) found facilitation when sound and electric shock were paired but no effect when light was paired with either sound or shock. These results may be understood using the scheme suggested by Hilgard (1933) to account for facilitation of the eyeblink reflex. Hilgard used light and sound stimuli slightly offset in time a...

We investigate the qualitative behavior of solutions of a Burgers-Boussinesq system – a reaction-diffusion equation coupled via gravity to a Burgers equation – by a combination of numerical, asymptotic and mathematical techniques. Numerical simulations suggest that when the gravity ρ is small the solutions decompose into a traveling wave and an accelerated shock wave moving in opposite directio...

Abstract Numerical simulations for the output pressure and shock response were performed using hydrocode MSC.DYTRAN to analyze effect of combustion characteristics main charges on a typical igniter. The results are in good agreement with experimental results. by changing type charges. show that differences gas production capacity have greater igniter than reaction rate.

Phenomenological reactive flow models for the shock initiation and detonation of solid high explosives, such as the Ignition and Growth model and the Johnson-Tang-Forest (JTF) model have been very successful in reproducing most of the main features of these reactive flows. The reaction rate expressions in these models depend upon the average compressions and pressures attained in the reacting e...

OBJECTIVE Myocardial injury during cardiac surgery is a major cause of perioperative morbidity and mortality. We determined whether perioperative statin therapy is cardioprotective in patients undergoing noncoronary artery cardiac surgery and the potential mechanisms. METHODS AND RESULTS One hundred fifty-one patients undergoing noncoronary artery cardiac surgery were randomly assigned to eit...

We report that streptococcal cell wall (SCW)-induced arthritis in rats, a T cell-dependent chronic, erosive polyarthritis, can be prevented by pretreatment of the rats with the mycobacterial 65-kD heat shock protein. This 65-kD protein shows extensive amino acid homology with prokaryotic and eukaryotic 65-kD heat shock proteins and is a ubiquitous bacterial common antigen. Both the clinical and...

A new exact solution of an oblique detonation is developed for the supersonic irrotational flow of an inviscid calorically perfect ideal gas, which undergoes a one-step, irreversible, exothermic, zero activation energy reaction as it passes through a straight shock over a curved wedge. The solution gives expressions for the velocity, pressure, density, temperature, and position as parametric fu...

BACKGROUND Extracorporeal shock wave therapy (ESWT) can modulate cell behavior through mechanical information transduction. Human periodontal ligament fibroblasts (hPDLF) are sensible to mechanical stimulus and can express pro-inflammatory molecules in response. The aim of this study was to evaluate the impacts of shock waves on interleukin-6 (IL-6), interleukin-8 (IL-8), monocyte chemotactic p...