INTRODUCTION We conducted a post-hoc analysis on the effect of recombinant factor VIIa (rFVIIa) on coagulopathic patients from two randomized, placebo-controlled, double-blind trials of rFVIIa as an adjunctive therapy for bleeding in patients with severe trauma. METHODS Blunt and penetrating trauma patients were randomly assigned to rFVIIa (200 + 100 + 100 microg/kg) at 0, 1, and 3 hours afte...

objective: thoracic trauma may be a life-threatening condition. flail chest is a severe chest injury with high mortality rates. surgery is not frequently performed and, in literature, data are controversial. the authors report their experience in the treatment of flail chest by an extracortical internal-external stabilization technique with kirshner’s wires (k-wires). methods: from 2010 to 2015...

conclusions this new suggested scale shows a better value to predict patients’ length of hospital stay compared to iss and niss. however, future studies with larger sample sizes and more confounding factors such as prehospital procedures, intubation and other procedures during admission, should be designed to examine these scoring systems and confirm the results of our study. background trauma ...

1Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran 2HIV/AIDS Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran 3Bactriology and Virology Department, Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, IR Iran 4Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz Universit...

recommend a target haemoglobin of 7 to 9 g/dl to initiate blood transfusion [1]. In their rationale the authors use a subgroup of trauma patients from the Transfusion Require ments in Critical Care study; however, patients with active blood loss were excluded from this trial. Expressing a current opinion about transfusion and trauma patients, in 2006 McIntyre and Hebert wrote: 'It is important ...

*Department of Radiation Oncology, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran **Student Research Committee, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran ***Endocrinology Research Center, Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran ****Shiraz Institute for Cancer Research, Shiraz University of Medical Sc...

Transfused platelets (plts) are either pooled random-donor platelet (plt) concentrates or single-donor apheresis plts. When stored for 5 days, all of these products are equally efficacious. A 10,000/microL prophylactic plt transfusion trigger has been documented to be both hemostatically efficacious and cost effective in reducing plt transfusion requirements. The optimal plt dose/transfusion is...

The objective of this study was to evaluate the utility and sensitivity of routine pelvic radiographs (PXR) in the initial evaluation of blunt trauma patients. A retrospective review was performed. One hundred seventy-four patients with a pelvic fracture who had computed tomography (CT) and PXR were included (average age, 36.1; average Injury Severity Score, 16.3). Nine (5%) patients died. Five...

Introduction: Trauma-induced coagulopathy (TIC) is a form of unique to trauma patients and associated with increased mortality. The complexity incomplete understanding TIC have resulted in controversies regarding optimum management. This review aims summarise the pathophysiology appraise established emerging advances management TIC. Methods: narrative based on literature search (MEDLINE databas...