Background. In recent years in Philadelphia, shigellosis has shifted from a disease primarily affecting children and women of childbearing age to one that more commonly affects males ≥13 years of age. Studies of similar shifts in other U.S. cities have concluded that increased incidence among adult males may result from outbreaks among men who have sex with men (MSM). Antibiotic resistance amon...

Shigella is a major cause of morbidity, mortality, and growth retardation for children in developing countries. Emergence of antibiotic resistance among Shigellae demands the development of effective medicines. Previous studies found that the endogenous antimicrobial peptide LL-37 is down-regulated in the rectal epithelium of patients during shigellosis and that butyrate up-regulates the expres...

OBJECTIVE In Vietnam, shigellosis/dysentery, typhoid fever, and cholera are important enteric diseases. To better understand their epidemiology, we determined temporal trends, seasonal patterns, and climatic factors associated with high risk periods in eight regions across Vietnam. METHODS We quantified monthly cases and incidence rates (IR) for each region from national surveillance data (19...

BACKGROUND Timely reporting of infectious disease cases to public health authorities is essential to effective public health response. To evaluate the timeliness of reporting to the Dutch Municipal Health Services (MHS), we used as quantitative measures the intervals between onset of symptoms and MHS notification, and between laboratory diagnosis and notification with regard to six notifiable d...

background and objectives: shigella plays an important role as a causative organism of acute gastroenteritis, in children and others. rapid emergence of antibiotic resistance warrants continuous monitoring of susceptibility pattern of bacterial isolates. we report here our findings about shigella spp. isolates and their drug resistance patterns in nepalese patients. materials and methods: the s...

Genital prolapse in the newborn is a rare clinical condition often times seen in association with congenital myelo-meningocele, or this could occur following shigellosis infection. We therefore report two neonates with rectal prolapse following diarrhea and utero-vaginal prolapse associated with congenital spinal bifida.

In 1979, British laboratories participating in the American of Clinical Pathologists' survey reported five cases of tuberculosis, four of chickenpox, four of salmonellosis or shigellosis, one malaria, and one hepatitis A infection. Microbiology workers were most affected, but at least six infections were not attributable to work. All cases recovered.

An investigation of two Shigella sonnei shigellosis outbreaks that occurred in a communal settlement indicated that the transmission of the pathogen was restricted to day-care classes and secondary infection of family members was minimal. Development of serotype-specific immunity following S. sonnei infection was observed among infected children.