​BACKGROUND: The clinical severity of disease in neurofibromatosis type 2 (NF2) is variable. Patients affected with a constitutional truncating NF2 mutation have severe disease, while missense mutations or mosaic mutations present with a milder attenuated phenotype. Genotype-derived natural history data are important to inform discussions on prognosis and management. METHODS We have assessed ...

INTRODUCTION The goal of our study was to characterize patients admitted to the hospital with hypothermia in a desert climate. METHODS This was a retrospective study (1999-2005) in a 1200-bed tertiary care hospital in southern Israel. Patients' data and weather condition (including mean day high and low temperatures, humidity, wind velocity and precipitation) within 48 hours before admission ...

Introduction Severity is a basic feature that defines the prognosis of a disease. FMF presents with a variety of clinic and laboratory manifestations affecting severity, and evaluation of prognosis is an elusive task. Different severity scores have been previously proposed for FMF, and commonly used ones include Mor, Pras and Tel Hashomer severity scores however recent studies showed that there...

Background In order to assess glaucoma severity and to compare the success of surgical and medical therapy and study outcomes, an objective and independent staging tool is necessary. A combination of information from both structural and functional testing is probably the best approach to stage glaucomatous damage. There has been no universally accepted standard for glaucoma staging. The aim of ...

AIM To determine the perinatal factors associated with initial illness severity (measured by the CRIB (clinical risk index for babies) score) and its relation to survival to discharge. METHODS A retrospective study was made of intensive care nursing records on 380 inborn babies, of less than 31 weeks gestation or 1501 g birthweight, admitted to one unit between 1984-6 and 1991-4. RESULTS Be...

INTRODUCTION Bronchiectasis (BC) is a multidimensional and etiologically diverse disease and, therefore, no single parameter can be used to determine its overall severity and prognosis. In this regard, two different validated scores are currently used to assess the severity of non-cystic fibrosis bronchiectasis (NCFB): the FACED score and the Bronchiectasis Severity Index (BSI). OBJECTIVE To ...

INTRODUCTION Non-cystic fibrosis bronchiectasis (NCFB) is a multidimensional disease, and no single isolated parameter is proved to have sufficient power for any overall determination of its severity and prognosis. OBJECTIVE To compare the results of the assessment of the NCFB severity with respect to its prognosis in the same patients by two different validated scores, i.e. the FACED score a...

INTRODUCTION Acute pancreatitis is inflammatory process of the pancreas associated with local and systemic complications. At present, there are lots of scores (such as Ransons, APACHE II, bedside index for severity in acute pancreatitis) that help us in predicting severity at the time of admission but these are time consuming or require complex calculation and are costly. MATERIAL AND METHODS...

BACKGROUND The Multiple Sclerosis Severity Score (MSSS) is obtained by normalising the Expanded Disability Status Scale (EDSS) score for disease duration and has been a valuable tool in cross-sectional studies. OBJECTIVE To assess whether use of age rather than the inherently ambiguous disease duration was a feasible approach. METHOD We pooled disability data from three population-based coh...

OBJECTIVE This study aims to help set domestic guidelines for administration of antivenom to envenomated patients after snakebites. METHODS This retrospective observational case series comprised 128 patients with snake envenomation. The patients were divided into two groups according to the need for additional antivenom after the initial treatment based on the traditional snakebite severity g...