Background & Aims: Multiple sclerosis (MS) is one of the chronic autoimmune diseases of the central nervous system with unknown etiology. The present study aimed to investigate the apoptosis and nitric oxide (NO) production of endothelial cells treated with serum of patients with MS and response to interferon beta (IFN- ) therapy. Methods: Human umbilical vein endothelial cells were treated wit...

The aim of this study was to measure umbilical blood androgen concentrations in a birth cohort using a highly specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay and assesses the effects of sex, labor, and gestational age on fetal androgen levels at birth. We performed a prospective cohort study of androgen concentrations in mixed arterial and venous umbilical cord serum fr...

umbilical and supraumbilical catheter insertion is a common procedure performed in the nicu. it is a safe and usually easy procedure devoid of serious mishaps, morbidity and mortality. complications such as hemorrhage, infection, hernia, evisceration, omphalitis, portal vein thrombosis and portal hypertension may occur after umbilical catheter insertion. other uncommon and rare complications re...

OBJECTIVE To analyze the impact of timing of clamping and obstetric, biological and socioeconomic factors on the iron stores of full-term newborns. METHODS Cross-sectional study between October 2011 and July 2012 in which hematological parameters were evaluated for newborns in Viçosa, MG, Southeastern Brazil. It involved collecting 7 mL of umbilical cord blood from 144 full-term not underweig...

Introduction:Maternal diabetes mellitus is associated with depleted fetal iron stores and this is proportionate to the degree of maternal control, presence or absence of diabetes-related complications, and is not related to maternal iron status. In this study, we aim to assess the effect of maternal diabetes on cord blood serum ferritin. Methods: The present prospective (case-control) study was...

OBJECTIVES To determine the effect of delayed umbilical cord clamping on Hb (haemoglobin) and bilirubin levels of neonates and to identify newborn babies with anaemia and refer them for treatment. METHODS This Randomized Controlled Trial was conducted in the Department of Obstetrics and Gynaecology, Unit V, Dow Medical College and Lyari General Hospital and Department of Pathology, Lyari Gene...