Currently, in patients with systemic lupus erythematosus (SLE) increasing attention is paid to the ovarian reserve evaluation, which can serve as one of markers a favorable response therapy and pregnancy planning. For this purpose, anti-Mullerian hormone (AMH) considered most sensitive marker, that reflect continuous growth small follicles. The article presents data on relationship serum levels...

PURPOSE With a widening arsenal of cancer therapies available, it is important to develop therapy-specific predictive markers and methods to rapidly assess treatment efficacy. We here evaluated the use of cytokeratin-18 (CK18) as a serum biomarker for monitoring chemotherapy-induced cell death in breast cancer. EXPERIMENTAL DESIGN Different molecular forms of CK18 (caspase cleaved and total) ...

Background: Beta thalassemia is one of the most common causes inherited disorder in world. In India, around 65000-70000 cases are present currently and every years 9000-10000 new added. Measurement serum ferritin level gives an idea about when to start iron chelation therapy, which will reduce concentration thereby prevents multiple organ damages. Methods: A prospective hospital based study was...

Kawasaki disease (KD) has complexly clinical features and laboratory parameters and there is no definitive biomarker for this disease and the therapy of KD also is complex and uncertain. In this study, 102 KD patients and 80 healthy controls were enrolled in this study and the serum microRNAs were detected by qRT-PCR. The results showed that, compared with KD patients with a good response to hi...

conclusions this case highlights the fact that fhr and ghd may coexist, with possible masking effect of one on the other, thereby misleading the approach, posing large impacts on therapy, which has historically been a difficult challenge in fhr patients. introduction coincided familial hypophosphatemic rickets (fhr) and hypopituitarism is a rare condition. growth hormone deficiency (ghd) evalua...

We monitored the effectiveness of lymphoma therapy by measuring the serum levels of soluble CD44std (sCD44std) and soluble CD44v6 (sCD44v6). Furthermore, we measured the level of soluble interleukin 2 receptor (sIL-2R). A total of 24 patients with non-Hodgkin's lymphoma were enrolled. sCD44std, sCD44v6, and sIL-2R on serum were measured using ELISA system. In all patients, only the sIL-2R level...

In the present study, serum vitamin B,2 determinations and various clinical and hematologic measurements were made on patients with chronic myelocytic leukemia before and during 6-MP or Myleran therapy and also at regular intervals during the first remission period. The results indicate that a reduction in total leukocytes following therapy is followed by a gradual lowering of serum vitamin B12...

In the present study, serum vitamin B,2 determinations and various clinical and hematologic measurements were made on patients with chronic myelocytic leukemia before and during 6-MP or Myleran therapy and also at regular intervals during the first remission period. The results indicate that a reduction in total leukocytes following therapy is followed by a gradual lowering of serum vitamin B12...

abstract background patients who are to receive chemotherapy require careful assessment of liver function prior to treatment to determine which drugs may not be appropriate, and which drug doses should be modified. following therapy abnormalities of liver function tests may be due to the therapy rather than to progressive disease, and this distinction is of critical importance. toxicity such as...

The prevalence of atrial fibrillation is high and comparable in both sexes. Such factors as differently expressed blood biomarkers women men may play a role the occurrence development thrombotic complications. To study markers inflammation platelet activation patients with non-valvular origin, receiving anticoagulant therapy having history complications without complications, depending on gende...