INTRODUCTION Brain derived neurotrophic factor (BDNF) has been implicated in memory, learning, and neurodegenerative diseases. However, the relationship of BDNF with cardiometabolic risk factors is unclear, and the effect of exercise training on BDNF has not been previously explored in individuals with type 2 diabetes. METHODS Men and women (N = 150) with type 2 diabetes were randomized to an...

OBJECTIVE To evaluate osteoprotegerin serum concentration (and compare with healthy controls), to estimate the relationship between serum osteoprotegerin and lipid parameters, insulin resistance, and selected inflammatory factors, and to assess the relationship between osteoprotegerin and intima media thickness in patients with metabolic syndrome. PATIENTS AND METHODS A total of 70 individual...

Introduction: Nowadays one of the most important problems of Thalassemia major patients is the additional load of iron and hemosiderosis, the most important consequence of which is deposited iron in myocardial tissue and the incidence of cardiomyopathy caused by hemochromatosis. The aim of this study was to determine the effect of concurrent (resistance-endurance) exercise on NT-pro BNP and...

Oral fructose has been shown to reduce the degree and duration of alcohol intoxication by increasing the rate of alcohol elimination from bloodstream. Fructose feeding has also been reported to induce insulin resistance and the resistance is characterized by increase in both blood glucose and triacylglycerol (TAG) levels. We report the synergistic effect of ethanol and fructose administration o...

BACKGROUND Fibroblast growth factor 19 (FGF19) and FGF21 are considered to be novel adipokines that improve glucose tolerance and insulin sensitivity. In the current study, we investigated serum FGF19 and FGF21 levels in patients with gestational diabetes mellitus (GDM) and explored their relationships with anthropometric and endocrine parameters. METHOD Serum FGF19 and FGF21 levels were dete...

Background: Irisin is a recently identified myokine that acts like adipokines. It has been revealed to be connected with insulin resistance (IR), obesity, and metabolic syndrome. Objective: To investigate serum, follicular fluid (FF), irisin, IR in lean, overweight, obese women undergoing the intracytoplasmic sperm injection (ICSI) cycle correlate them oocyte embryo quality. Methods: Ninety inf...