Objective: Compare the pharmacokinetics of vaginal progesterone gel (Crinone 8%, 90 mg) with that of oral progesterone (Prometrium, 100 mg). Design: Open-label, randomized, parallel-group protocol. Setting: Outpatient clinic. Patient(s): Twelve healthy postmenopausal women. Intervention(s): Six subjects each were randomized to receive progesterone, which was administered either as 90 mg of prog...

Introduction: Acne is a chronic inflammatory disorder of the pilosebaceous unit with differential pathogenesis. To elucidate roles hormones in acne pathogenesis, we conducted study to evaluate serum testosterone, estradiol, and progesterone levels women vulgaris. Methods: We cross-sectional descriptive study, 175 vulgaris were exam...

Measurement of progesterone in saliva offers several advantages when compared to assays of serum progesterone, especially when ovarian activity is being assessed. Most published methods for the determination of progesterone in saliva are based on assays developed in research centers, which employ "in-house" reagents that are critically dependent on supplies of highly selected antisera. In this ...

BACKGROUND Ovarian follicular activity in serial hormone profiles has been reported in up to 86% of patients with primary ovarian insufficiency (POI). In most of these studies, patients had a short duration of amenorrhea or irregular menstrual cycles which could influence the occurrence of spontaneous follicular activity. The aim was to study the incidence of follicular activity in serial hormo...

Objectives: Uterine artery Doppler is frequently used in the first trimester and it one of more effective measurement methods prediction preeclampsia intrauterine growth restriction (IUGR). Progesterone a hormone that quite various indications obstetrics gynecologic practice. We aimed to investigate influence progesterone on uterine pulsatility index (PI) at 11–14 gestational weeks. Material me...

The Community Bureau of Reference of the European Communities has produced four batches of lyophilized serum Certified Reference Materials, two for cortisol (CRM 192 and 193) and two for progesterone (CRM 347 and 348). For cortisol, one of the pools consisted of serum from healthy blood donors, whereas the second batch was supplemented with pure cortisol. The progesterone Reference Materials co...

Background: Endometriosis is a chronic hormone-dependent inflammatory disease determined by the presence of foci endometrial tissue outside uterine cavity. Genetic factors occupy leading position in etiopathogenesis this disease. With endometriosis, there pronounced hormonal imbalance sex hormones both lesion and body sick woman as whole. The aim study:To study associations polymorphism hormone...

Background: Progesterone (PG) is an essential hormone in the process of implantation and pregnancy maintenance. Frozen-thawed embryo transfer (FET) being performed worldwide. This study was designed to investigate whether serum progesterone levels on day prior 5 frozen-thawed hormonally prepared endometrium correlates with outcomes. Materials Methods: A single center longitudinal observational ...

BACKGROUND Polycystic-ovary syndrome (PCOS) is a reproductive illness characterized by hyperandrogenism and anovulation. Using hyperandrogenized mice, it was demonstrated that the oral administration of incremental dose of follicle stimulating hormone (FSH) attenuated some of PCOS characteristics. This work aimed to study the effect of ultra-low doses of combined FSH and progesterone orally adm...