Diabetes mellitus caused by insulin resistance is prompted obesity. Neuropeptide Nesfatin-1 was identified in several organs, including the central nervous system and pancreatic islet cells. peptide appears to be involved hypothalamic circuits that energy homeostasis control food intake. Adiponectin a plasma collagen-like protein produced adipocytes have been linked development of (IR), diabete...

Background/ObjectiveInsulin autoimmune syndrome (IAS) is a very rare cause of hypoglycemia presenting with recurrent fasting or postprandial episodes elevated serum insulin levels and autoantibodies. The objective this case to highlight the importance considering IAS in patients hypoglycemia.Case ReportWe present an 81-year-old female who presented symptoms hypoglycemia. She was found have hype...

BACKGROUND Few data have been published on the association of variables of the insulin resistance syndrome and serum total homocysteine (tHcy), a putative risk factor for cardiovascular morbidity, in representative samples of total populations or in Hispanic Americans. METHODS To describe the distributions of serum tHcy concentration and variables associated with insulin resistance in Mexican...

OBJECTIVE Circulating leptin levels correlate positively with the degree of obesity and prolonged hyperinsulinaemia increases serum leptin levels. Moreover, insulin secreting beta-cells express functional leptin receptors indicating a functional relationship between leptin and insulin. The aim of this study was to examine the relationship between fasting serum leptin levels and measures of insu...

Background: To determine the relationship between serum leptin and insulin resistance in obese Pakistani subjects. Methods: In this observational study fifty healthy obese and overweight subjects were selected by nonprobability convenience sampling. Age, sex, height, weight and body mass index (BMI) of subjects were recorded. Fasting plasma glucose, serum leptin and insulin were measured. Fifty...

Objective: Crocinisa saffron constituent with a potent anti-oxidant activity. The present study investigated the effects of crocin and insulin treatments (alone or in combination) on cardiac function and pathology in diabetic rats. Materials and Methods: Diabetes was induced by intraperitoneal (i.p.) injection of streptozotocin (STZ, 50 mg/kg). Thereafter, crocin (5, 10 and 20 mg/kg, i.p.), sub...