Background Atopic dermatitis (AD) is a chronic inflammatory dermatosis of the skin that leads to xerosis and pruritus. It is known that the serum levels of total immunoglobulin E (IgE) appear to be higher in patients with more severe AD. Changes in skin barrier also demonstrate that there is increased susceptibility to skin infections in AD, including by viruses, such as herpes simplex virus (H...

Background Atopic dermatitis is a common chronic skin disorder which is a subset of atopy. Atopy refers to a genetic predisposition to respond immunonologically to allergens which are generally harmless, causingover production of immunoglobulin E (IgE) antibodies. IgE synthesis is dependent on the activation of CD4+ Th2 subset and their secretion of cytokines including IL 4 and IL 13. This stud...

Background: Job’s syndrome or hyper-immunoglobulin E (IgE) (HIES) is an extremely rare primary immunodeficiency disease with approximate annual incidence of less than 1/1000000. It characterized by recurrent cold staphylococcal infections, unusual eczematous dermatitis, severe lung and extensively high concentrations the serum antibody IgE. Case Presentation: A typical case a family history Kaw...

Two experiments were conducted to examine effects of d-á-tocopherol (vitamin E) on colostrum immunoglobulin G (IgG) titers and preweaning lamb performance. Trial 1 consisted of 86 Suffolk ewes receiving either no vitamin E (control) or 1500 IU vitamin E on d-28 prepartum. From the 86 ewes, a subset of 25 ewes was randomly chosen for an intensive analysis of ewe serum and colostrum IgG and lamb ...

The binding of bilirubin was analysed in the serum of a patient with unusual myeloma. This patient presented an acquired Von Willebrand's disease due to the presence of a ternary complex formed by one molecule of myeloma immunoglobulin G and two molecules of albumin (Harlé et al. La Presse Médicale 19, 1661-1664 (1990)). The binding characteristics of bilirubin--number of sites (n) and associat...

This report describes the diagnosis, follow-up, and problems measuring serum immunoglobulin E (IgE) levels in a case of IgE myeloma with 20-yr survival. Serum and urine protein electrophoresis, immunofixation, and the N Latex IgE test were used to characterize the monoclonal proteins. The diagnosis of multiple myeloma in a 56-yr-old man was based on 5.4 g/24 h of monoclonal free lambda chain in...

objective vitamin e is a major lipid-soluble antioxidant. it has been demonstrated that vitamin e supplementation has a beneficial effect against coronary heart disease (chd). this study to investigate the effects of coronary risk factors on serum vitamin e status in patients with dyslipidaemia. materials and methods this tertiary care hospital; case - control study was comprised 237 dyslipidae...

Serum obtained after immunization with an O18 polysaccharide-toxin A conjugate vaccine was evaluated for the estimation of protective levels of anti-O-specific lipopolysaccharide (LPS) immunoglobulin G (IgG) antibody against bacteremia and death caused by a homologous serotype of Escherichia coli K1 strains. Passive transfer of rabbit serum conferred significant protection from a lethal E. coli...