Objective: Microalbuminuria and hypertension are the risk factors for diabetic nephropathy, and increased levels of liver enzymes are prevalent among diabetic patients. The aim of this research was to examine the effects of Crocus sativus supplementation on ...

Purpose: We aimed to investigate dragon fruit (Hylocereus polyrhizus) extract effectiveness by creating a nephropathy model with contrast media toxicity after dehydration and furosemide administration rats. 
 Methods: Total 36 male Sprague dawley rats were randomly allocated into 6 groups (n: 6). At the end of experiment kidney organs blood was taken for histopathologic biochemical analyze...

We studied the usefulness of preoperative resistance index to select patients who will benefit most from renal stenting. Sixty-two patients underwent renal stenting. All had chronic renal insufficiency with serum creatinine values ranging from 1.5 to 2.5 mg/dL and blood urea nitrogen between 80 and 107 mg/dL. All treated renal artery stenosis were >70%. Reduction in blood pressure in the early ...

In previous papers (1, 2) it was shown that when the urine volume output falls below about 0.35 ml. per minute, the urine becomes " maximally" concentrated with respect to urea. The urea concentration of the urine is constant below this critical volume, and thus the urea clearance (U V/B) varies directly and quantitatively with the urine volume (V). In an effort to analyze the mechanism of rena...

Purpose: To investigate the reno-protective properties of Cinnamomum tamala against gentamicininduced nephrotoxicity in rabbits. Methods: Rabbits were randomly divided into four groups (n = 6) including Group-1 (normal saline), Group-2 (gentamicin, 80 mg/kg/day), Group-3 (C. tamala, 200 mg/kg/day) and Group-4 (gentamicin, 80 mg/kg/day and C. tamala, 200 mg/kg/day). Body weight, blood urea nitro...

C-peptide levels can initially be normal or increased in type 2 diabetes mellitus (T2DM), which is connected to insulin resistance; however, as the condition progresses, these may fall. According studies, kidney failure has its primary cause, accounting for 44% of all new cases. In addition, it's critical strictly regulate blood sugar and lower protein intake. Along with insulin, pancreas produ...

INTRODUCTION It has been suggested that hypertension (HTN) is associated with certain target organ damage (TOD) and related clinical conditions. On the other hand, left ventricular hypertrophy (LVH) has been considered as an independent risk factor of cardiovascular events and death. The aim of this study was to examine the relationship between HTN-induced LVH and TOD (retinopathy and renal fai...

PATIENT Female, 17 FINAL DIAGNOSIS: Acute kidney injury Symptoms: Flank pain • nausea • vomiting MEDICATION Isotretinoin Clinical Procedure: Acne treatment Specialty: Nephrology Objective: Unknown etiology. BACKGROUND Isotretinoin is widely used for the treatment of acne that is unresponsive to topical therapy. Despite its efficacy, isotretinoin has various adverse effects, including cheili...

the aim of this study was to investigate the protective role of vitamin e against vancomycin-induced nephrotoxicity. there are some evidences that oxidative injury could be involved in its pathogenesis. vitamin e at doses of 50, 100 and 200 mg/kg were administered s.c. to rats 30 min prior to i.p. injection of 200 mg/kg vancomycin (van). drug administrations were done every 12 h for 7 days. aft...

BACKGROUND The aim of this study was to investigate the urine levels of human kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL), N-acetyl-β-D-glucosaminidase (NAG), and liver-type fatty acid-binding protein (L-FABP) in children with iron-deficiency anemia (IDA). MATERIAL AND METHODS Thirty-five children with IDA and 32 matched healthy controls were recruited....