Abstract Sporadic occurrence of congenital portosystemic shunt (PSS) at a rate ∼1 out 10 among C57BL/6 mice, which are widely used in biomedical research, results aberrancies serologic, metabolic, and physiologic parameters. Therefore, mice with PSS should be identified as outliers research. Accordingly, we sought methods to, reliably efficiently, identify mice. Serum total bile acids ≥ 40 µM i...

Our survey of kidney and liver transplant centers in New York State found a wide variation among transplant centers in evaluation and screening for HIV risk and infection among prospective living donors. Survey results underscore the need to standardize practices. A recent transmission of human immunodeficiency virus (HIV) from a living donor to a kidney recipient revealed a possible limitation...

BACKGROUND AND OBJECTIVES Serologic tests for granulocyte antibodies, i.e., the granulocyte agglutination test and the granulocyte immunofluorescence test, require panels of typed granulocytes that cannot be preserved for more than a few hours. We have developed a new method in which granulocyte antigens, extracted into saline containing 3% sucrose, are coated onto U-type Terasaki plates. With ...

Commercial serologic assays accurately detect adult Helicobacter pylori infection. Their use in children remains controversial. An ELISA to detect H. pylori IgG in children was developed and compared with three commercial assays. ELISA standardization was done with sera from all ages and validation was done with another cohort of sera with known H. pylori status. Three commercial serologic assa...

Current diagnosis of chronic Chagas disease relies on serologic detection of specific immunoglobulin G against Trypanosoma cruzi. However, the presence of parasites detected by polymerase chain reaction (PCR) in patients without positive conventional serologic testing has been observed. We determined the prevalence and clinical characteristics of persons with seronegative results and T. cruzi D...

The aim of this study was to determine the diagnostic value of a serologic test for Helicobacter pylori (H. pylori) in pediatric population presenting with abdominal pain suspected of peptic disease. We conducted a preospective cross sectional study. There were 202 children with abdominal pain. Serologic BM test using Helisual Quick test kit was performed. All patients then underwent endoscopic...

Neuromyelitis optica (NMO) is an autoimmune disease that primarily targets astrocytes. Autoantibodies (NMO-IgG) against the water channel protein, aquaporin 4 (AQP4), are a serologic marker in NMO patients, and they known to be responsible for pathophysiology of disease. In brain, AQP4 mainly expressed astrocytes, especially at end-feet, where form blood-brain barrier. Following interaction bet...

Abstract Background Frequent and rapid development of myelopathy has been reported in individuals with human T-lymphotropic virus type 1 (HTLV-1) infection following solid organ transplantation. There is no information regarding HTLV-2, a closely related that often infects injection drug users. Methods This study includes retrospective analysis all consecutive transplants performed during the l...

Background: Ultrasound is established as a diagnostic tool in salivary glands for obstructive diseases such sialolithiasis and tumors. Concerning inflammatory non-sialolithiasis-caused obstruction, much fewer data are available. In recent years, technical development has allowed better assessment of the gland parenchyma, knowledge about intraductal pathologies increased considerably, which prov...