Background Cyclic nucleotide-gated (CNG) channels are members of the superfamily of pore loop cation channels that are activated by the binding of cGMP or cAMP. The channels are important cellular switches which transduce changes in intracellular levels of cyclic nucleotides into changes of the membrane potential and the Ca2+ concentration. CNG channels play a central role in the signal transdu...

in this literature, a combined method has been employed to simultaneously reducesmoke (soot) and oxide of nitrogen (nox) and maintain the performance parameters of dieselengine. this includes creating an air jet by designing an air-cell inside the piston body, advancedinjection timing and using cold exhaust gas recirculation. the tested engine was an mt4.244engine that worked as natural aspirat...

this study presents a computational study of mixture formation, flame front movement, combustion process and emission formation at the various spray angles and number holes in a direct injection diesel engine. this work is carried out in a direct injection om355 diesel engine at four and five holes with 130
, 135
and 140
spray angles. the amount of fuel injected per cycle is constant at all s...

nitrogen oxides (nox) contribute to a wide range of environmental effects including the formation of acid rain and destroy ozone layer. in-cylinder high temperature flame and high oxygen concentration are the parameters which affect the nox emissions. the egr system is a very effective way for reducing nox emission from a diesel engine (via reduction of these parameters), particularly at the hi...

Direct injection diesel engines are in service for both heavy duty vehicles, light duty vehicles not only in the fields of agriculture and transport sectors, but also stationary engines consume maximum percentage of petroleum based fuels and have the evident benefit of a higher thermal efficiency than all other engines. However, the D. I. Diesel engine emits significant amount of pollutants suc...

Cyclic nucleotide-gated (CNG) channels link intracellular cyclic nucleotides to changes in membrane ionic conductance in a variety of physiological contexts. In the retina, in addition to their central role in phototransduction, CNG channels may be involved in nitric oxide signaling in bipolar neurons or in the hyperpolarizing synaptic response to glutamate in ON-type (depolarizing) bipolar cel...

The effect of conagenin (CNG) on myelosuppression induced by antitumor agents was investigated. The daily administration of CNG prevented reduction in the number of platelets (PLT) observed in peripheral blood of mice given mitomycin C (10 mg/kg) but did not prevent reduction in the number of leukocytes (WBC). The effect on PLT was also confirmed in mice given cyclophosphamide (100 mg/kg). In m...