The estradiol (E2), estrogen receptor-α (ERα), testosterone (T), and androgen receptor (AR) can contribute to anxiety, but whether they are associated with the reversion of prenatal adverse outcomes remains unclear. Here, we tested the interactive effects of prenatal maternal restraint stress and early postnatal short-term maternal separation on adult male mandarin vole (Microtus mandarinus) be...

social anxiety disorder is a common anxiety disorders in childhood and adolescence. adolescence is a period during which the individual believes will lead to different outcomes. the aim of this study was to compare early maladaptive schemas in two groups of adolescents with social anxiety disorder and normal adolescents. the present study was causal-comparative. population was consisted of all ...

The rodent maternal separation (MS) paradigm is frequently used to investigate the impact of early-life conditions in the offspring. One critical issue is whether the effects seen in the offspring are a result of maternal contact deprivation and/or altered pup-directed maternal behavior. To address this question we used an innovative approach with a qualitative analysis of pup-retrieval strateg...

OBJECTIVE to investigate homotypic and heterotypic longitudinal patterns of symptoms of separation anxiety disorder (SAD), generalized anxiety disorder (GAD), social phobia (SoPh), panic disorder (PD), and obsessive compulsive disorder (OCD) in young adolescents from the Dutch general population. METHOD 2,067 individuals (51.4% girls) from a Dutch community sample, who were assessed for the f...

where a(t) is a locally integrable function of /. We call equation (1) oscillatory if all solutions of (1) have arbitrarily large zeros on [0, oo), otherwise, we say equation (1) is nonoscillatory. As a consequence of Sturm's Separation Theorem [21], if one of the solutions of (1) is oscillatory, then all of them are. The same is true for the nonoscillation of (1). The literature on second orde...

Daily separation of rat pups from their mothers while the preweaning period has an impact on behavior and stress response of pups. We hypothesized that maternal separation may create a depression-like state in mother rats from which we separate the rat pups and decrease their reproductive function and fertility. Also, we aimed to evaluate the transmission degree of depression and anxiety across...

This study examined whether the occurrence and timing of parental separation or divorce was related to trajectories of academic grades and mother- and teacher-reported internalizing and externalizing problems. The authors used hierarchical linear models to estimate trajectories for children who did and did not experience their parents' divorce or separation in kindergarten through 10th grade (N...

BACKGROUND Anxiety and attention-deficit/hyperactivity (ADH) problems are common in adolescence, often co-occur, and are characterised by high heterogeneity in their phenotypic expressions. Although it is known that anxiety and ADH problems correlate, the relationships between subtypes of anxiety and ADH problems have been scarcely investigated. METHODS Using a large population sample of adol...