Acute paraquat (PQ) toxicity induces redox cycling leading to fatality in both man and animals with clinical management being supportive therapy due lack of specific effective antidote. This study thus aimed at determining the sero-biochemical pathological changes induced by acute PQ administration male rats mitigating role sodium selenite. Forty were used for grouped into 5 eight viz: Group I ...

PURPOSE In this study, we investigated the biochemical pharmacology of pirenoxine (PRX) and catalin under in vitro selenite/calcium- and ultraviolet (UV)-induced lens protein turbidity challenges. The systemic effects of catalin were determined using a selenite-induced cataractogenesis rat model. METHODS In vitro cataractogenesis assay systems (including UVB/C photo-oxidation of lens crystall...

Newborn lambs depend on their dams for passive transfer of immunoglobulins, primarily IgG, for protection from harmful pathogens until their own immunological defenses have developed. Previous studies have suggested that supplementation with Se results in a modest increase in IgG concentration in serum of newborn calves and lambs. To evaluate the effect of the Se source and supplementation rate...

The bioavailability of Se from raw and cured selenomethionine-enriched (Se-enriched) salmon fillets was assessed in Se-deficient male albino rats (Mol: Wist). A low-Se Torula yeast feed was supplemented with 0, 50, 100, 150 or 200 microg Se/kg as sodium selenite or as Se from raw or cured Se-enriched salmon. The diets were fed to weanling rats for 10 and 30 d. Bioavailability of Se was assessed...

Selenium (Se) occurs in various forms in soils, including inorganic selenite and selenate and organic selenomethionine. Plant uptake of the inorganic, but not the organic forms, has been studied extensively. Organic-Se uptake was therefore examined in two-grooved milkvetch (Astragalus bisulcatus (Hook.) Gray), a Se-accumulating forb, and western wheatgrass (Pascopyrum (Rydb.) Love), a non-Se ac...

Intervention trials with different forms of selenium are under way to assess the effects of selenium supplements on the incidence of cancer and other diseases. Plasma selenium biomarkers respond to selenium administration and might be useful for assessing compliance and safety in these trials. The present study characterized the effects of selenium supplementation on plasma selenium biomarkers ...

Cataract is clouding of the eye lens that reduces the amount of incoming light and results in deteriorating vision. Blindness is thought to reach 75 million by 2020. Of these, unoperated cataract may be expected to account for at least 35 million. Thus, the burden of cataract is increasing remorselessly. Embelica officinalis is reported to have a very good antioxidant property and thus we hypot...

Renal failure is accompanied by oxidative stress, which is caused by enhanced production of reactive oxygen species and impaired antioxidant defense. The suggested therapeutical interventions aimed at reducing oxidative stress in chronic renal failure patients are as follows: 1) the use of biocompatible membranes, ultrapure dialysate, and removal of endogenous foci of infection; 2) haemolipodia...

One feeding trial and two balance studies were conducted to study the effects of adding arsanilic acid or vitamin E (E) upon utilization of natural or supplemental selenium (Se) (from sodium selenite) in the diet. Eighty weanling pigs were assigned at random to eight dietary treatments in a 23 factorial design. The basal corn-soybean meal diet (containing .036 ppm Se and 6 IU E/kg) was fed alon...

EDWARDS, P. R. AND EWING, W. H. 1955 Identification of Enterobacteriaceae. Burgess Publishing Company, Minneapolis, Minnesota. EYRE, J. W. H. 1908 Milroy lectures on melitensis septicemia. Lancet, 1, 1747. LEVINE, M. AND TANIMOTO, R. H. 1954 Antagonisms among enteric pathogens and coliform bacteria. J. Bacteriol., 67, 537-541. NORTH, W. R. AND BARTRAM, M. T. 1953 The efficiency of selenite brot...