Background and purpose Many drugs can worsen myasthenia symptoms. The clinician usually relies on cautionary lists compiled according to case reports. We intended provide a quantitative basis for risk comparison within the groups of antiepileptic, antidepressant, neuroleptic, sedative drugs. Methods extracted adverse drug reaction (ADR) counts (total related) from these calculated reporting odd...

conclusions midazolam could be used as a safe and effective drug for conscious sedation, general anaesthetic premedication and the treatment of seizures during dental treatment. however, further research on paediatric patients would be beneficial. evidence acquisition to conduct this review of the literature, pub-med and scopus were searched using the following terms: midazolam, oral, transmuco...

Remimazolam is a new ultrashort-acting benzodiazepine with fast onset, quick recovery, and few side effects, such as hypotension respiratory depression. It expected to be safe effective for wide range of patients undergoing intravenous sedation dental procedures. The aim this literature review was evaluate clinical outcomes remimazolam, including method administration, level at the dose require...

BACKGROUND Sedation or anesthesia is used to facilitate many cases of an estimated 45 million diagnostic and therapeutic medical procedures in the United States. Preclinical studies have called attention to the possibility that sedative-hypnotic drugs can increase pain perception, but whether this observation holds true in humans and whether pain-modulating effects are agent-specific or charact...