OBJECTIVE To examine the predictive value of clinical examination, laboratory tests and Doppler ultrasound examination in systemic lupus erythematosus (SLE) and/or antiphospholipid syndrome (APS) pregnancies. METHODS A prospective study of 116 pregnancies followed in a single tertiary referral centre. Outcomes analysed were fetal/neonatal death and adverse pregnancy outcome. Univariate analys...

It was thought to be impossible to prolong the pregnancy in a case of uterine rupture in the second trimester. We encountered a case of rupture of the pregnant uterus in early mid-trimester, which we repaired with suture and overlapping of collagen fleece coated with fibrin glue, resulting in pregnancy prolongation until the 34th week. Our case and five previously reported cases were reviewed. ...

background: alcohol is a potent teratogen and alcohol use in pregnancy and the periconception period can cause many complications in mother, fetus and neonate.  discussion: alcohol in the mother's blood passes through the placenta to the baby through the umbilical cord. drinking alcohol during pregnancy can cause miscarriage, stillbirth, and a range of lifelong disorders. alcohol-related birth ...

We evaluated the influence of maternal pre-pregnancy body mass index (BMI), based on reported pre-pregnancy weight and height, on blood pressure (BP) levels during pregnancy by using information from a prospective cohort of 1733 women recruited before 20 weeks' gestation. Maternal antenatal BP values were abstracted from medical records, and we evaluated the mean BP differences according to BMI...

introduction: ramadan fasting is prescribed by holy quran for every able-bodied, adult muslim and is considered an essential practice for all muslims including pregnant women. the aim of this study was to determine the effect of ramadan fasting on neonatal anthropometric measurements during the third trimester of pregnancy. method: this is a cross-sectional study, carried out on 300 delivering ...

conclusions misoprostol plus letrozole was more effective for inducing abortion in the first trimester of pregnancy compared to misoprostol alone. results the complete abortion rate was 69.7% in the misoprostol and letrozole group and 30.3% in the misoprostol group. incomplete abortion was 32.4% in the misoprostol and letrozole group, and 67.6% in the misoprostol group (p = 0.004). bleeding, ce...

We report the echocardiographic identification of cardiac tumours in antenatal life in a pregnancy where the father was known to have tuberous sclerosis. This allowed termination of an affected pregnancy in the second trimester.

BACKGROUND Excessive gestational weight gain (GWG) is associated with adverse pregnancy outcomes. In non-pregnant populations, low leptin levels stimulate positive energy balance. In pregnancy, both the placenta and adipose tissue contribute to circulating leptin levels. We tested whether maternal leptin levels are associated with subsequent GWG and whether this association varies depending on ...

BACKGROUND Analysis of circulating RNA in the plasma of pregnant women has the potential to serve as a powerful tool for noninvasive prenatal testing and research. However, detection of circulating RNA in the plasma in an unbiased and high-throughput manner has been technically challenging. Therefore, only a limited number of circulating RNA species in maternal plasma have been validated as pre...

OBJECTIVE We longitudinally examined the changes of brachial to ankle distensibility using pulse wave velocity (PWV) throughout pregnancy and its difference between normal pregnancy and pregnancy-induced hypertension (PIH) groups. STUDY DESIGN One hundred and eighty-three pregnant women were included in this study. The PWV examinations were performed in a longitudinal way during the first, se...