نتایج جستجو برای: scd14

تعداد نتایج: 398  

Journal: :The Open Dentistry Journal 2022

Background: Caries experience, oral hygiene status, and salivary sCD14 level are three essential factors to analyse individual dental caries development risk. Therefore, regular effective instruction (OHI) is for prevention. Objective: This study aims the differences in levels before after OHI. Methods: An observational with intervention was conducted on 40 samples of each group taken an accide...

2013
Arturo Gonzalez-Quintela Manuela Alonso Joaquin Campos Luis Vizcaino Lourdes Loidi Francisco Gude

BACKGROUND AND AIM Assessment of serum concentration of lipopolysaccharide (LPS)-binding protein (LBP) has been suggested as a useful biomarker to indicate activation of innate immune responses to microbial products. We investigated LBP concentrations and associations with demographics, lifestyle factors, and common metabolic abnormalities in adults. We also examined if LBP concentrations were ...

2016
Sergio Serrano-Villar Talia Sainz Zhong-Min Ma Netanya S. Utay Tae Wook-Chun Surinder Mann Angela D. Kashuba Basile Siewe Anthony Albanese Paolo Troia-Cancio Elizabeth Sinclair Anoma Somasunderam Tammy Yotter Steven G. Deeks Alan Landay Richard B. Pollard Christopher J. Miller Santiago Moreno David M. Asmuth Guido Silvestri

Whether initiation of antiretroviral therapy (ART) regimens aimed at achieving greater concentrations within gut associated lymphoid tissue (GALT) impacts the level of mucosal immune reconstitution, inflammatory markers and the viral reservoir remains unknown. We included 12 HIV- controls and 32 ART-naïve HIV patients who were randomized to efavirenz, maraviroc or maraviroc+raltegravir, each wi...

2013
Mathieu F. Chevalier Gaël Petitjean Catherine Dunyach-Rémy Céline Didier Pierre-Marie Girard Maria Elena Manea Pauline Campa Laurence Meyer Christine Rouzioux Jean-Philippe Lavigne Françoise Barré-Sinoussi Daniel Scott-Algara Laurence Weiss

Impairment of the intestinal barrier and subsequent microbial translocation (MT) may be involved in chronic immune activation, which plays a central role in HIV pathogenesis. Th17 cells are critical to prevent MT. The aim of the study was to investigate, in patients with primary HIV infection (PHI), the early relationship between the Th17/Treg ratio, monocyte activation and MT and their impact ...

Journal: :Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2008
Malin Fagerås Böttcher Thomas Robert Abrahamsson Mats Fredriksson Ted Jakobsson Bengt Björkstén

The immunological composition of breast milk differs between mothers. The reasons for these differences and the consequences for the breast-fed infants are poorly understood. The aim of this study was to evaluate the effect of probiotic Lactobacillus reuteri supplementation on the immunological composition of breast milk in relation to sensitization and eczema in the babies. Total IgA, secretor...

2014
Ranjini Valiathan Maria J. Miguez Bijal Patel Kristopher L. Arheart Deshratn Asthana

BACKGROUND The influence of tobacco smoking on the immune system of HIV infected individuals is largely unknown. We investigated the impact of tobacco smoking on immune activation, microbial translocation, immune exhaustion and T-cell function in HIV infected individuals. METHOD HIV infected smokers and non-smokers (n = 25 each) with documented viral suppression on combination antiretroviral ...

2013
Karin Simonin-Le Jeune André Le Jeune Stéphane Jouneau Chantal Belleguic Pierre-François Roux Marie Jaguin Marie-Thérèse Dimanche-Boitre Valérie Lecureur Caroline Leclercq Benoît Desrues Graziella Brinchault Jean-Pierre Gangneux Corinne Martin-Chouly

BACKGROUND Early in life, cystic fibrosis (CF) patients are infected with microorganisms. The role of macrophages has largely been underestimated in literature, whereas the focus being mostly on neutrophils and epithelial cells. Macrophages may however play a significant role in the initiating stages of this disease, via an inability to act as a suppressor cell. Yet macrophage dysfunction may b...

2018
Maximilian Muenchhoff Michael Healy Ravesh Singh Julia Roider Andreas Groll Chirjeev Kindra Thobekile Sibaya Angeline Moonsamy Callum McGregor Michelle Q. Phan Alejandro Palma Henrik Kloverpris Alasdair Leslie Raziya Bobat Philip LaRussa Thumbi Ndung'u Philip Goulder Magdalena E. Sobieszczyk Mohendran Archary

This observational study aimed to describe immunopathogenesis and treatment outcomes in children with and without severe acute malnutrition (SAM) and HIV-infection. We studied markers of microbial translocation (16sDNA), intestinal damage (iFABP), monocyte activation (sCD14), T-cell activation (CD38, HLA-DR) and immune exhaustion (PD1) in 32 HIV-infected children with and 41 HIV-infected childr...

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