BACKGROUND Pilonidal disease is a common and usually minor disease. Although wide excisional surgery has been common practice, there are more simple alternatives. This review focused on the aetiology and management of pilonidal disease. METHODS A comprehensive review of the literature on pilonidal disease was undertaken. MEDLINE searches for all articles listing pilonidal disease (1980-2010) ...

BACKGROUND Hirsutism is a common clinical condition with different etiologies. Many of these patients have frank or subclinical abnormalities in the adrenal and ovarian steroidogenesis. The disease may be associated with other clinical signs of hyperandrogenism. The objective of this study was to investigate the clinical features of hirsutism and its etiologic factors in premenopausal Iranian w...

The prevalence of polycystic ovaries in the women who had had recurrent miscarriages was high (82%). Although the number of parous control women was small, their prevalence of polycystic ovaries (18%) was similar to that observed in a much larger population of normal women (22%).3 The normal serum luteinising hormone and urine pregnanediol-3a-glucuronide concentrations suggest that the endocrin...

To measure the concentration of testosterone (T) that is not bound to sex-steroid-binding protein (SBP) in plasma, we quantified by radioimmunoassay the T in the supernates of plasma samples after precipitation with 50%-saturated ammonium sulfate. The concentrations of non-SBP-bound T. directly measured with this assay, correlated significantly (P less than 0.001) with those deduced from measur...

BACKGROUND Flutamide is an antiandrogen devoid of other hormonal effects, except for a decrease in the secretion of adrenal androgens such as dehydroepidandrosterone sulphate (DHEA-s) and androstenedione. AIM To assess the effectiveness of flutamide in the treatment of hirsutism, used as monotherapy or combined with oral contraceptives (OC). PATIENTS AND METHODS Women with peripheral hirsut...

Pediculosis BLOCKINpubis BLOCKIN(PP) BLOCKINis BLOCKINinfestation BLOCKINwith BLOCKINpubic lice of the species Phthirus pubis. There are no ratial differences in its incidence and the infestation is generally common (1). Direct contact is the BLOCKINprimary BLOCKINsource BLOCKINof BLOCKINtransmission. BLOCKINIn BLOCKINadults, BLOCKINPP most frequently occurs as a sexually transmitted disease (S...

OBJECTIVE Clinical manifestations and metabolic risk factors may differ in ethnic subgroups of patients with polycystic ovary syndrome (PCOS). DESIGN Retrospective trans-sectional study. PATIENTS One thousand and two premenopausal women with the diagnoses hirsutism or PCOS were divided according to ethnicity: Caucasian (CA, n = 784), Middle East (ME, n = 190), Asian (n = 14) and others (n =...

Amenorrhoea is common in women with non-alcoholic chronic liver disease, but little is known about its causes or consequences. We investigated 12 young women with non-alcoholic chronic liver disease and amenorrhoea and compared them with 11 healthy age matched controls studied in the follicular phase of the menstrual cycle. None of the patients had raised serum concentrations of follicle stimul...

BACKGROUND Polycystic ovary syndrome (PCOS) is a common endocrine condition affecting women of reproductive age and characterized by chronic anovulation, hyperandrogenism, and polycystic ovaries. There are no published data on this syndrome in Libyan patients. AIMS AND OBJECTIVES To assess the frequency of clinical and biochemical features of PCOS in our patient population, and to compare thi...