Introduction. Lymphoepithelioma-like carcinoma (LELC) of the salivary gland is a rare tumor. Currently, surgery with or without radiotherapy is the recommended treatment for all salivary gland carcinomas. However, in contrast to other high-grade salivary gland carcinomas, LELCs are considered radiosensitive. There are only a few published reports of radiotherapy alone for the treatment of saliv...

BACKGROUND To determine the incidence and prevalence of salivary gland tumours in the province of Valparaíso, Chile. MATERIAL AND METHODS Retrospective review of salivary gland tumours diagnosed between the years 2000 and 2011 from four local pathology services. Information on demographics and histopathology were retrieved from the medical records. RESULTS The study sample consisted of 279 ...

In this work, we investigated the activity of the platelet activating factor acetyl hydrolase (PAF-AH) in the salivary gland homogenates and saliva of Rhodnius prolixus. PAF-AH activity in the salivary gland homogenates was lower than in the saliva. Preliminary characterization of the enzyme demonstrated that it hydrolyzed the substrate 2-thio-PAF, was detectable just in 1 pair of salivary glan...

Immunologically, the parotid salivary gland is an effector site that secretes large quantities of polyspecific Abs into the saliva, mainly of the IgA isotype. It is considered to be part of the common mucosal immune system but the inductive site for the Ab-producing cells of the salivary gland has not yet been clearly identified. The origin and diversity of cells of B lineage can be investigate...

Pleomorphic adenoma (PA), the most common salivary gland tumor, accounts for 54 to 65% of all salivary gland neoplasias and 80% of the benign salivary gland tumors. It most frequently affects the parotid gland, followed by the submandibular and the minor salivary glands. Microscopically, mucous, sebaceous, oncocytic and squamous metaplasia, sometimes with the formation of keratin pearls, may be...

Heterotopic salivary-gland tissue Fistula in the lower neck Congenital abnormality Abstract Heterotopic islands of salivary-gland tissue are rare and have been described in a number of sites in the head and neck. We describe a patient with salivary-gland fistulas in the lower third of the neck, without evidence of any other congenital abnormalities. The appearance of sinuses in association with...

OBJECTIVES/HYPOTHESIS To create a novel model for development of a tissue-engineered salivary gland from human salivary gland cells that retains progenitor cell markers useful for treatment of radiation-induced xerostomia. STUDY DESIGN A three-dimensional (3D) hyaluronic acid (HA)-based hydrogel scaffold was used to encapsulate primary human salivary gland cells and to obtain organized acini-...

INTRODUCTION Salivary gland tumors (SGTs) are important parts of human neoplasms. The most common SGT is pleomorphic adenoma and the most common malignant SGTs are mucoepidermoid carcinoma and adenoid cystic carcinoma (ACC). Metastasis-associated genes 1 (MTA1), a member of the nucleosome remodeling and histone deacetylation complex, is one newly discovered gene which recruits histone deacetyla...

ABSTRACT Introduction: Pleomorphic adenoma is the most common tumor of the salivary gland. The tumor most commonly arises in the parotid or submandibular salivary glands. Infrequently, it arises from minor salivary glands. Minor salivary gland tumors are mostly malignant. Case Report: We report four cases of pleomorphic adenoma of hard palate. All four cases range from 30–45 years. All were ben...