OBJECTIVE Circulating cortisol and psychosocial stress may contribute to the pathogenesis of obesity and metabolic syndrome (MS). To evaluate these relationships, a cross-sectional study of 369 overweight and obese subjects and 60 healthy volunteers was performed and reviewed the previous literature. DESIGN AND METHODS Overweight and obese subjects had at least two other features of Cushing's...

The aims of this study were to identify the perceived sources of stress in final-year dental students studying in a private dental school in Riyadh, Saudi Arabia, using a modified dental environmental stress (DES) scale and to correlate these findings, at various times in the semester, with the level of acute stress measured with salivary cortisol as a biomarker. A total of forty final-year stu...

Objective: This study aims to determine the relationship among demographic, clinical characteristics, and psychosocial factors related salivary cortisol in children with leukemia. Methods: research was a descriptive cross-sectional design. The sample leukemia Dr. Sardjito General Hospital Yogyakarta from January February 2018 size 30 respondents who had met inclusion criteria, aged 6-18 years, ...

Objective. To clarify the effect of Lactobacillus plantarum 299v on the salivary cortisol and salivary IgA levels in young adults under examination stress. Design. Forty-one students with an upcoming academic exam were included in a randomized double-blind, placebo-controlled study. The probiotic bacteria or the placebo product was administered in capsules once a day during 14 days. Saliva was ...

Oral lichen planus (OLP) is a chronic inflammatory disease. Ulcerative types of OLP are symptomatic and are considered premalignant lesions. The etiology of OLP is unknown and there is controversy over the role of stress as an etiologic factor of OLP. This study investigated the salivary cortisol level and stress intensity in a sample of Iranian OLP patients. Saliva samples were taken from 30 O...

It is often difficult for instructors teaching laboratory courses in behavioral neuroscience to find appropriate experiments that can ethically examine biological parameters in human participants. In most instances, the default experiments that allow students to act as both experimenter and subject tend to be electrophysiological in nature (e.g., EEG, GSR, etc.). We report here the use of an ex...

Hypothalamic-Pituitary-Adrenal (HPA) axis and its end product cortisol have been extensively investigated in patients with depressive disorders for many years. Recently, salivary alpha-amylase (sAA) had emerged as a new biomarker non-invasive more convenience protocol measuring sympathetic activity which were also associated depression. Selective Serotonin Reuptake Inhibitor (SSRI) is antidepre...

Dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) are anabolic prehormones involved in the synthesis of testosterone. Both have been shown to exert neuroprotective effects during stress. In this randomized, controlled, double-blind field study, we examined the effects of a 12-day DHEA regimen on stress indices in military men undergoing survival training. Forty-eight men were randomized to...

Familial caregivers of patients with Alzheimer's disease exhibit reduced quality of life and increased stress levels. The aim of this study was to investigate the effects of an 8-week yoga and compassion meditation program on the perceived stress, anxiety, depression, and salivary cortisol levels in familial caregivers. A total of 46 volunteers were randomly assigned to participate in a stress-...

PURPOSE To investigate the pre- and post-heelstick stress response patterns of infants and to identify related maternal factors. MATERIALS AND METHODS Fifty-two mothers and their 57 infants were studied. Stress response patterns in neonates were collected by measurements of pulse rate, oxygen saturation, and salivary cortisol. Maternal demographic factors and awakening saliva were collected. ...