Long-term heparin treatment causes osteoporosis through an as yet undefined mechanism. To investigate this phenomenon, we treated rats with once daily subcutaneous injections of heparin (in doses ranging from 0.25 to 1.0 U/g) or saline for 8 to 32 days and monitored the effects on bone both histomorphometrically and by serial measurements of urinary type 1 collagen cross linked-pyridinoline (PY...

background: it has been known that brain-derived neurotrophic factor (bdnf) is involved in neural survival and long term memory (ltm). here we hypothesized that bdnf as a potent neurotrophic factor might modulate amnestic effect induced by morphine. objectives: the aim of this study was to examine whether infusion of exogenous bdnf in the ca1 regions of the dorsal hippocampi could ameliorate me...

A serologically active substance was extracted from cells of Hemophilus aegyptius with dilute NAOH. This substance directly hemagglutinated human erythrocytes. The activity of this material was demonstrated at a near neutral pH and was precipitated at acid pH. Preliminary biochemical determination showed this serologically active material to be predominately polysaccharide. Davis, Pittman, and ...

Pedogenesis and clay mineralogy of soils and rock samples were studied in a transect of calcareous, gypsiferous, saline soils and sediments of Bakhtegan lake bank in southern Iran. The main objectives of study were to determine the occurrence of clay minerals and factors controlling their distribution pattern and relative abundance in soils and parent materials. The soil parent material is high...

The generation of activity-evoked extracellular alkaline shifts has been linked to the presence of external Ca(2+) or Ba(2+). We further investigated this dependence using pH- and Ca(2+)-selective microelectrodes in the CA1 area of juvenile, rat hippocampal slices. In HEPES-buffered media, alkaline transients evoked by pressure ejection of RS-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic ...

Little is known about uranium, U(VI), transport in alkaline and saline solutions. However understanding U(VI) mobility in these conditions is critical due to the storage of U(VI) at high pH and ionic strengths (I). To this end we have studied the geochemical processes taking place in a reservoir, and during transport through quartz sand packed columns. The results show that at pH 10.5 and 11.5 ...