نتایج جستجو برای: s3
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Tamm-Horsfall protein (THP) is a glycoprotein expressed exclusively in thick ascending limbs (TAL) of the kidney. We recently described a novel protective role of THP against acute kidney injury (AKI) via downregulation of inflammation in the outer medulla. Our current study investigates the mechanistic relationships among the status of THP, inflammation, and tubular injury. Using an ischemia-r...
Extra diastolic heart sounds are produced as a result of increased stiffness and decreased compliance of the left ventricle. The third heart sound (S3) occurs 0.12 to 0.16 seconds after the second heart sound in early diastole (Figure 1). Of the many proposed theories, the most likely explanation is that excessive rapid fi lling of a stiff ventricle is suddenly halted, causing vibrations that a...
In his 1974 thesis, Martin Scharlemann constructed a fake homotopy equivalence from a closed smooth manifold f : Q → S3 × S1#S2 × S2, and asked the question whether or not the manifold Q itself is diffeomorphic to S3 × S1#S2 × S2. Here we answer this question affirmatively. In [Sc] Scharlemann showed that if Σ3 is the Poincaré homology 3-sphere, by surgering the 4-manifold Σ× S, along a loop in...
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