نتایج جستجو برای: s regions
تعداد نتایج: 1037645 فیلتر نتایج به سال:
384 mothers out of the mothers dwelling in Kabudrahang district and Nozheh Airforce Station who had, at last, one infant under 24 months of age were selected in the study. Of these, 196 cases were...
marek's disease (md) is a common lymphoproliferative disease of chickens, usually characterized by mononuclear cellular infiltration in different organs. the disease is caused by a herpes virus and is transmissible. md has been a common, important problem for poultry industry worldwide, as well as, in our country, iran. the aim of present study was to have an estimation of the incidence of...
Activation-induced cytidine deaminase (AID) initiates Ab class-switch recombination (CSR) in activated B cells resulting in exchanging the IgH C region and improved Ab effector function. During CSR, AID instigates DNA double-strand break (DSB) formation in switch (S) regions located upstream of C region genes. DSBs are necessary for CSR, but improper regulation of DSBs can lead to chromosomal t...
Class switch recombination (CSR) occurs by an intrachromosomal deletion whereby the IgM constant region gene (Cmu) is replaced by a downstream constant region gene. This unique recombination event involves formation of double-strand breaks (DSBs) in immunoglobulin switch (S) regions, and requires activation-induced cytidine deaminase (AID), which converts cytosines to uracils. Repair of the ura...
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