the right ventricle (rv) is a complex structure with abstruse function that reveals important differences when compared to the left ventricle (lv), so it cannot be described as a simple geometric form and achromatic physiology. as an inference from this fact, in the present review, we aim to describe rv structure including the embryology, anatomy, and physiology and present a functional, hemody...

Right heart failure in pulmonary arterial hypertension (PH) is associated with mechanical ventricular dyssynchrony, which leads to impaired right ventricular (RV) function and, by adverse diastolic interaction, to impaired left ventricular (LV) function as well. However, therapies aiming to restore synchrony by pacing are currently not available. In this proof-of-principle study, we determined ...

ccurrence of severe congestive heart failure or requirement for ntra-aortic balloon pump or cardiopulmonary resuscitation (p .0081). The main and novel findings of this report are: 1) RV involveent in TLVABS is common, transient, and, when present, ortends a longer and more critical hospitalization course as ompared with patients with isolated LV involvement; and 2) RV nvolvement, when present,...

Human milk (HM) is rich in oligosaccharides (HMO) that exert prebiotic and anti-infective activities. HM feeding reduces the incidence of rotavirus (RV) infection in infants. Herein, the anti-RV activity of oligosaccharides was tested in an established in vitro system for assessing cellular binding and viral infectivity/replication, and also tested in a newly developed, acute RV infection, in s...

The purpose of this paper is to review several modalities that can be helpful in evaluating right-ventricular (RV) function. We have investigated the role of functional imaging in analysis of regional RV function and in selection of RV region of interest (ROI). From this we have derived a method to determine the RV ejection fraction using a single RV ROI. The analysis is performed in a modified...

Rotavirus (RV) is a common cause of severe gastroenteritis (GE) in children worldwide. Live oral RV vaccines protect against severe RVGE, but the immune correlates of protection are not yet clearly defined. Inner capsid VP6 protein is a highly conserved, abundant, and immunogenic RV protein, and VP6-specific mucosal antibodies, especially IgA, have been implicated to protect against viral chall...

Diastolic function is a major determinant of ventricular performance, especially when loading conditions are altered. We evaluated biventricular diastolic function in lambs and studied possible load dependence of diastolic parameters [minimum first derivative of pressure vs. time (dP/dt(min)) and time constant of isovolumic relaxation (tau)] in normal (n = 5) and chronic right ventricular (RV) ...

BACKGROUND Recognizing that inhibitors of phosphodiesterase type 5 (PDE5) are increasingly employed in patients with pulmonary hypertension and right ventricular (RV) failure, we examined PDE5 expression in the human RV and its impact on myocardial contractility. METHODS AND RESULTS Tissue extracts from the RV of 20 patients were assayed for PDE5 expression using immunoblot and immunohistoche...