In 2005, the acceptance rate for renal replacement therapy (RRT) in adults in the UK was 108 pmp and this was derived from 100% complete data returns for the UK. From 2001 to 2005 there has been a 7.3% rise in the acceptance numbers in those 42 renal units with full reporting throughout that period. The median age of patients starting RRT in England has increased from 63.8 years in 1998 to 65.2...

Successful disease management requires a rapid and sensitive diagnosis method that can recognize early infection even before the manifestation of its clinical signs. The only available field diagnostic tests for foot-and-mouth disease (FMD) are lateral flow devices, commonly known as chromatographic strips. Low sensitivity and inability to detect FMD virus (FMDV) at the serotype level are limit...

In the pre-RRT era, many patients with oliguric ARF died of hyperkalaemia or fluid overload. With the advent of RRT, it quickly became apparent that these complications could be averted or treated by the initiation of RRT1. However, just as in chronic renal failure, precise indications for initiation of RRT have never been established2. In the modern era, it is conventional to initiate RRT when...

BACKGROUND Acute kidney injury (AKI) is a common problem in critically ill patients treated in the intensive care unit (ICU) and is associated with high mortality, particularly when renal replacement therapy (RRT) is required. Our aim was to investigate the risk factors for AKI requiring RRT (AKI-RRT). METHODS In our retrospective, multi-centre, observational study, we analysed 14,672 consecu...

Acute kidney injury (AKI) independently increases morbidity and mortality in children admitted to the hospital. Renal replacement therapy (RRT) is an essential therapy in the setting of AKI and fluid overload. The decision to initiate RRT is complex and often complicated by concerns related to patient hemodynamic and thermodynamic instability. The choice of which RRT modality to use depends on ...

BACKGROUND Relatively few data exist on the burden of end-stage renal disease (ESRD) and use of renal replacement therapy (RRT)-a life-saving therapy-in developing regions. No study has quantified the proportion of patients who develop ESRD but are unable to access RRT. METHODS We performed a comprehensive literature search to estimate use and annual initiation of RRT worldwide, and present t...

Background Patients on chronic intermittent renal replacement therapy (RRT) are at risk for infection with carbapenem-resistant Enterobacteriaceae (CRE). However, the impact of RRT on outcomes after CRE infections remains to be defined. Here we perform a comparison of outcomes for CRE-infected patients with preserved renal function compared with CRE-infected patients on RRT. Methods Cases and...

Abstract Background Serological testing based on different antibody types are an alternative method being used to diagnose SARS-CoV-2 and has the potential of having higher diagnostic accuracy compared current gold standard rRT-PCR. Therefore, objective this review was evaluate IgG IgM point-of-care (POC) lateral flow immunoassay (LFIA), chemiluminescence enzyme (CLIA), fluorescence enzyme-link...

In 2018, World Kidney Day (WKD) and International Women's Day coincide. The WKD editorial focuses on women's kidney health. The European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry Annual Report 2015 summary provides an excellent snapshot of renal replacement therapy (RRT) epidemiology and women in Europe. The WKD editorial reports a lower incidence of RRT...

OBJECTIVES Describe the incidence, prevalence and survival of patients needing renal replacement therapy (RRT) for end-stage renal disease (ESRD) due to diabetes mellitus (DM)-related glomerulosclerosis or nephropathy (diabetic nephropathy, DN) in the Netherlands. DESIGN Using the national registry for RRT (RENINE-registry), data of all Dutch individuals initiating RRT for ESRD and having DN ...