Octreotide, an effective treatment for acromegaly, induces gall bladder stones in 13-60% of patients. Because knowledge of stone composition is essential for studies of their pathogenesis, treatment, and prevention, this was investigated by direct and indirect methods in 14 octreotide treated acromegalic patients with gall stones. Chemical analysis of gall stones retrieved at cholecystectomy fr...

Background Gall bladder volume can have clinical and therapeutic implications and possibly affect certain pathophysiological mechanisms of many diseases affecting the gallbladder including gall stones. Objective The objective of the study was to establish baseline indices of gallbladder volume for the Sikkimese population and determine its correlation with age, sex and Body Mass Index. Method A...

Gall stone ileus is a mechanical bowel obstruction caused by passage of gall stones from the biliary system through a biliaryenteric fistula with impaction within lumen of the bowel. It is an uncommon complication of biliary stone disease, accounting for only 2% of all cases of intestinal obstruction. Gall stone ileus is, however, more common in the elderly and accounts for approximately 25% of...

Repeated daily injections of the somatostatin analogue, octreotide (SMS201-995, Sandostatin) are an effective treatment for acromegaly, but lead to gall stone formation in about 50% of cases during longterm treatment. This is probably because of impaired gall bladder contraction. This study examined whether the timing of intermittent injections in relation to meals, or alternatively, continuous...

root-knot nematodes, meloidogyne spp., are one of the important plant parasitic nematodes of tomato in the world. the most suitable control method of plant parasitic nematodes is the use of resistance sources and tolerant cultivars. in the earlier studies, the results showed thatonly 2% (19 out of 537 varieties) were resistant and tolerant to the root knot nematodes. in the supplementary studie...

We have investigated the possibility that the abnormally decreased gall bladder contraction after meals in patients with coeliac disease might result in part from an abnormality in the gall bladder response to endogenous cholecystokinetic hormones--for example, cholecystokinin and motilin--rather than solely from decreased secretion of such hormones. Eight patients with untreated coeliac diseas...

The postprandial contractions of the gall bladder result from the interaction of neurohormonal factors but their relative contribution is unknown. This study was designed to determine the role of cholecystokinin (CCK) in gall bladder contractions using a highly selective and potent CCK-receptor antagonist, CR-1505 (loxiglumide) in healthy men either infused with exogenous CCK in graded doses (1...

The common soil bacteria Agrobacterium tumefaciens and Agrobacterium rhizogenes are unique genetic pathogens capable of fundamentally redirecting plant metabolism in order to generate macroscopic tissue masses (crown galls and hairy roots, respectively) which support the growth of large populations of Agrobacteria. Central to pathogenesis is the horizontal transfer of a suite of oncogenes from ...

As a result of the control of the flow of bile into the duodenum largely by tonus and movements of the duodenum, bile intermittently enters the gall bladder where it is concentrated and undergoes other changes. The gall bladder empties itself of its content through the cystic duct (1) by the washing out of its contents by bile from the liver, (2) by the elasticity or contractile mechanism of it...