Members of the carotenoid cleavage dioxygenase family catalyze the oxidative cleavage of carotenoids at various chain positions, leading to the formation of a wide range of apocarotenoid signaling molecules. To explore the functions of this diverse enzyme family, we have used a chemical genetic approach to design selective inhibitors for different classes of carotenoid cleavage dioxygenase. A s...

2,4,5-Trihydroxytoluene (THT) oxygenase from Burkholderia sp. strain DNT catalyzes the conversion of THT to an unstable ring fission product. Biochemical and genetic studies of THT oxygenase were undertaken to elucidate the mechanism of the ring fission reaction. The THT oxygenase gene (dntD) was previously localized to the 1.2-kb DNA insert subcloned in the recombinant plasmid designated pJS76...

The plant growth regulator, abscisic acid (ABA), is synthesized via the oxidative cleavage of an epoxy-carotenoid. Specifically, a double bond is cleaved by molecular oxygen and an aldehyde is formed at the site of cleavage in both products. The Vp14 gene from maize encodes an oxidative cleavage enzyme for ABA biosynthesis and the recombinant VP14 protein catalyzes the cleavage reaction in vitr...

The acid-catalyzed ring-opening reactions of a cyclopropanated 3-aza-2-oxabicylic alkene using alcohol nucleophiles were investigated. Although this acid-catalyzed ring-opening reaction did not cleave the cyclopropane unit as planned, this represent the first examples of ring-openings of cyclopropanated 3-aza-2-oxabicyclo[2.2.1]alkenes that lead to the cleavage of the C-O bond instead of the N-...

Flavanones, Catabolites, Peroxidases, Degradation, Substitution Pattern Peroxidases were shown to be responsible for the degradation of flavanones as occuring after application of these substrates to plant cell suspension cultures. — Comparative studies with various flavanones and horseradish peroxidase showed that only 4'-hydroxyflavanones will be catabolized peroxidatically. — Intensive analy...

in this paper, we study some ring theoretic properties of the amalgamated duplication ring $rbowtie i$ of a commutative noetherian ring $r$ along an ideal $i$ of $r$ which was introduced by d'anna and fontana. indeed, it is determined that when $rbowtie i$ satisfies serre's conditions $(r_n)$ and $(s_n)$, and when is a normal ring, a generalized cohen-macaulay ring and finally a filter ring.

in this paper, we introduce a class of $j$-quasipolar rings. let $r$ be a ring with identity. an element $a$ of a ring $r$ is called {it weakly $j$-quasipolar} if there exists $p^2 = pin comm^2(a)$ such that $a + p$ or $a-p$ are contained in $j(r)$ and the ring $r$ is called {it weakly $j$-quasipolar} if every element of $r$ is weakly $j$-quasipolar. we give many characterizations and investiga...

Cytokinesis requires a tight coordination between actomyosin ring constriction and new membrane addition along the ingressing cleavage furrow. However, the molecular mechanisms underlying vesicle trafficking to the equatorial site and how this process is coupled with the dynamics of the contractile apparatus are poorly defined. Here we provide evidence for the requirement of Rab1 during cleavag...

Due to its artificial and unnatural structure, Israeli society has since the beginning of its establishment, been a context for the emergence of different kinds of cleavages and tensions. This state of affairs has endangered the political stability of the Israeli regime. The present research is trying to answer this question: what is the effect of religious-secular cleavages in Israel on the fu...