The case of a 52-yr-old female with rheumatoid arthritis and HIV who developed massive, progressive, cavitary pulmonary nodules is described. Multiple diagnostic bronchoscopies and lung biopsies failed to demonstrate the presence of any microorganisms. Pathological analysis showed palisading histiocytes with necrobiosis consistent with rheumatoid nodules. The effect of co-existing HIV infection...

OBJECTIVES To describe the epidemiological profile of patients with extra-articular manifestations of rheumatoid arthritis (ExRA) from an university-affiliated rheumatology center; to report the prevalence of ExRA and to compare it with available data; and to identify, if possible, ExRA predictors. METHODS This study reviewed 262 medical charts of patients previously diagnosed with rheumatoid...

Background: Previous studies showed that one of the complications of rheumatoid arthritis disease was auditory disorder. The goal of the present study was to compare the auditory status in patients with rheumatoid arthritis and healthy individuals. Methods: In the present case-control study, 30 normal persons and 60 persons with rheumatoid arthritis with mean age of 46.72 and standard deviatio...

We present a case of hepatocellular carcinoma (HCC), showing an atypical "nodule-in-nodule" appearance on ultrasonogram (US). In general, a "nodule-in-nodule" appearance is found as a hyperechoic tumor containing a hypoechoic nodule. In the present case, however, there was a hyperechoic subnodule in the center of the tumor, which was surrounded by a hypoechoic tumor area. Histologically, the su...

Metastatic cancer of the umbilicus, known as Sister Mary Joseph nodule, is typically associated with visceral malignancy. It is an uncommon and rare presentation. It indicates disseminated disease and poor prognosis. Physicians need to be aware of this rare clinical condition so that they can promptly diagnose the primary cancer.

Although the lesions of rheumatoid arthritis occur throughout the body tissues, it is the synovial membrane which shows the most constant and usually the earliest changes. The characteristic features revealed by the light microscope are proliferation of synovial lining cells, infiltration with inflammatory cells including collections of plasma cells and lymphocytes, and increased vascularity. A...

PURPOSE To determine the prevalence, clinical characteristics and nature of subfoveal nodules in Coats' disease and the associated impact on the long-term visual outcome. METHODS Consecutive cases of Coats' disease with foveal exudation were retrospectively reviewed. The presence of a subfoveal nodule or macular fibrosis was recorded. Clinical characteristics, retinal imaging, and outcome wer...

right wrist. Neurological exami nation revealed that he had anomia, visual agnosia, mild right central facial palsy, right hemiparesis (Medical Research Council, MRC, grade 4/5), and right hemihypesthesia of all sensory modalities. Laboratory findings were unremarkable except for an elevated level of rheumatoid factor (238 IU/ml). A brain MRI scan disclosed 3 mass lesions in the bilateral tempo...

background: sonoelastography is a new ultrasound method which could be helpful to determine which thyroid nodule is malignant. we designed this study to evaluate the accuracy of sonoelastography in differentiating of benign and malignant thyroid nodules in iranian patients. methods: forty thyroid nodules in forty consecutive patients who had been referred for sonography‑guided fine‑needle aspir...