INTRODUCTION Preeclampsia (PE) is a pregnancy-related disorder characterized by hypertension (HT) and proteinuria noticeable after 20 weeks of gestation. PE is now considered as a cardiovascular disease risk factor and a number of studies have shown that experiencing PE increases the prevalence of various cardiovascular risk factors, such as metabolic syndrome and HT. In this study, we aimed to...

Background Few studies have documented the blood group antigens in the population of eastern India. Frequencies of some common alleles and haplotypes were unknown. We describe phenotype, allele, and haplotype frequencies in the state of West Bengal, India. Methods We tested 1,528 blood donors at the Medical College Hospital, Kolkata. The common antigens of the ABO, Rhesus, and Kell blood grou...

Rabbit polyclonal antibodies were raised against synthetic peptides corresponding to hydrophilic regions of the human Rhesus (Rh) IX cDNA-encoded polypeptide predicted to be extracellularly or intracellularly exposed in the topologic model of the Rh blood group protein. Four antibodies encompassing residues 33-45 (MPC1 ), 224-233 (MPC4), 390-404 (MPC6), and 408-41 6 (MPC8) were characterized an...

Human monoclonal antibodies (MoAbs) directed against the blood group Rh(D), (c), and (E) antigens produced by Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines have been used to characterize the Rh components of human red cell membranes and to determine whether the Rh(D), (c), and (E) epitopes are carried by distinct polypeptides. After immunoprecipitation with the anti-Rh(D) antib...

Dear Sir, We appreciate the importance given to our recent paper "Some reflections on the Code of Ethics of the International Society of Blood Transfusion"1 (ISBT) as reflected in the commissioning of Flanagan's editorial2. However, Flanagan asserts that our position, which has been carefully put together from our different backgrounds in transfusion (AF) and philosophy (CDB), arises from "Farr...

Human monoclonal antibodies (MoAbs) directed against the blood group Rh(D), (c), and (E) antigens produced by Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines have been used to characterize the Rh components of human red cell membranes and to determine whether the Rh(D), (c), and (E) epitopes are carried by distinct polypeptides. After immunoprecipitation with the anti-Rh(D) antib...

Of all blood group systems, anti Rh antibodies are the commonest cause of haemolytic disease of the newborn (HDN) and its diagnosis and management plan is well established. Also immunization with 'D' antigen can be effectively prevented by prophylactic use of anti-D Immunoglobulin. Therefore its prevalence has declined but now less common alloantibodies are frequently encountered posing differe...

Takashi Kitano, Satoshi OOta and Naruya Saitou (1999) Molecular evolutionary analyses of the Rh blood group genes and Rh50 genes in mammals. Zoological Studies 38(4): 379-386. All mammals probably possess the Rh blood group gene and its homologous Rh50 gene coded membrane proteins. In this study, we compared nucleotide sequences of Rh and Rh50 genes for primates and rodents. We found that the r...

Objectives. A prospective study was carried out to compare vaginal hysterectomy (VH) and robotically assisted hysterectomy (RH) for benign gynecological disease. Materials and Methods. All patients who underwent hysterectomy from March 2010 to March 2012 for a benign disease were included. Patients' demographics per and post surgery results were collected from medical files. A questionnaire was...