We identified a clinical isolate of Escherichia coli displaying an unusual, emerging phenotype; piperacillin/tazobactam (TZP)-resistant, 3rd generation cephalosporin-susceptible. Prior to treatment with TZP, TZP-susceptible E. was isolated from the same patient. Hyperproduction class A β-lactamase has previously been linked this phenotype, but mechanism hyperproduction in isolates lacking promo...

The purpose of this study was to examine the association of the BstUI RFLP C/T (rs 12722) and DpnII RFLP C/T (rs 13946) COL5A1 polymorphisms, individually and as haplotypes, with anterior cruciate ligament ruptures in recreational skiers. Subjects were 138 male recreational skiers with surgically diagnosed primary anterior cruciate ligament ruptures. The control group consisted of 183 apparentl...

background zoonotic cutaneous leishmaniasis (zcl) is polymorphic disease that may show various clinical manifestations. objectives this study investigates the determination of genetic variation within the species of leishmania major isolates from new cases in chabahar, a port city in southeast iran (situated at the iran-pakistan border). migration in this region indicates that leishmaniasis is ...

background: in most cases, prostatitis can be caused by a bacterial agent such as ureaplasma urealyticum. considering to the cumbersome of the culture method for the detection of ureaplasma species in clinical samples such as prostate; pcr method that is faster and more appropriate than the cultivation methods, can be utilized for the detection of u. urealyticum and u. parvum. pcr-rflp method c...

Introduction: Angiotensin-converting enzyme 2 (ACE2) is the central receptor of coronavirus disease 2019 (COVID-19) in host cells. Genetic polymorphisms ACE2 gene may promote cardiovascular and systemic inflammatory injury a patient affected by COVID-19. Thus, genetic background account for substantial inter-individual diversity illness susceptibility or severity. Our study was conducted to fin...

Hereditary hemochromatosis (HH) is a common autosomal disorder of iron metabolism mainly affecting Caucasian populations. Three recurrent disease-associated mutations have been detected in the hemochromatosis gene (HFE): C282Y, H63D, and S65C. Although HH phenotype has been associated with all three mutations, C282Y is considered the most relevant mutation responsible for hemochromatosis. Clini...