BACKGROUND Afterdrop, defined as the precipitous reduction in core temperature after cardiopulmonary bypass, results from redistribution of body heat to inadequately warmed peripheral tissues. The authors tested two methods of ameliorating afterdrop: (1) forced-air warming of peripheral tissues and (2) nitroprusside-induced vasodilation. METHODS Patients were cooled during cardiopulmonary byp...

CONTEXT The benefits of therapeutic hypothermia as a treatment for traumatic brain injury (TBI) remain unclear. OBJECTIVE To explore the effects of depth, duration, and rate of rewarming after discontinuation of hypothermia on mortality and neurologic outcome in adults after TBI. DATA SOURCES An electronic search of MEDLINE (OVID), EMBASE, Current Contents, the Cochrane library and a hand s...

Postharvest chilling injury (PCI) is a physiological disorder that contributes to the global loss and waste of fruit vegetables. Ectopic expression C-Repeat Binding Factor (CBF) transcription factors in tomato (Solanum lycopersicum L.) alleviates vegetative injury, but their influence on PCI unknown. We developed dexamethasone (DEX)-inducible system with aim limiting high ectopic Arabidopsis th...

PURPOSE Seizures are common in critically ill neonates. Both seizures and antiepileptic treatments may lead to short term complications and worsen the outcomes. Predicting the risks of seizure reoccurrence could enable individual treatment regimens and better outcomes. We aimed to identify EEG signatures of seizure reoccurrence by investigating periictal electrographic features and spectral pow...

Cat heart muscles preserved in normal Tyrode's solution at 4°C for prolonged periods were investigated by recording the transmembrane potentials after rewarming to 37°C. The cell membranes were gradually hyperpolarized during rewarming, the maximum hyperpolarization being reached within a few hours. The amplitude of resting potentials obtained at a maximally hyperpolarized stage was largest for...