Abstract Sample pretreatment is one of the most crucial and error-prone steps an analytical procedure; it consents to improve selectivity sensitivity by sample clean-up pre-concentration. Nowadays, arousing interest in greener sustainable chemistry has increased development microextraction techniques as alternative preparation procedures. In this review, we aimed show two different categorizati...

Praeruptorin D (PD), a major pyranocoumarin isolated from Radix Peucedani, exhibited antitumor and anti-inflammatory activities. The aim of this study was to investigate the pharmacokinetics and tissue distribution of PD in rats following intravenous (i.v.) administration. The levels of PD in plasma and tissues were measured by a simple and sensitive reversed-phase high-performance liquid chrom...

A reliable chromatographic strategy is crucial for the extraction of target compounds from natural sources as it related to preparation efficiency, well purity compounds. In this study, medium-pressure normal-phase liquid chromatography and high-pressure reverse-phase were combined prepare purify ergosterol Tulasnellaceae sp. Gymnadenia orchidis. First, was extracted three times (2.0 L 2 h each...

We report a common methodology for determining three antiarrhythmic drugs: disopyramide, lidocaine, and quinidine. Alkalinized serum and internal standard (p-chlorodisopyramide) are extracted into dichloromethane, the organic phase is evaporated, and the redissolved residue is injected onto a reversed-phase column (micron Bondapack C18). Quantitation is via peak-height ratios of analyte vs inte...

A simple and rapid analytical method was established for detection of anabolic agents, zeranol and alpha-trenbolone and beta-trenbolone residues in cattle muscle and liver. This method consisted of aqueous acetonitrile extraction and successive solid-phase extraction with a tandem connected octadecyl (C18)-aminopropyl (NH2) cartridge, followed by on-line clean-up using multidimensional HPLC wit...

A simple and sensitive solid-phase extraction method for separation and preconcentration of trace amount of four nonsteroidal anti-inflammatory drugs (naproxen, indomethacin, diclofenac, and ibuprofen) using Fe3O4 magnetic nanoparticles modified with cetyltrimethylammonium bromide has been developed. For this purpose, the surface of MNPs was modified with cetyltrimethylammonium bromide (CTAB) a...