The effect of adrenalectomy on 7,12-dimethyl benz(a)anthracene-induced mammary tumor growth was studied in Sprague-Dawley female rats. Weekly measure ments revealed that adrenalectomy significantly increased both mammary tumor size and number and elevated serum prolactin levels as compared to the intact controls. Daily injection of 1 mg hydrocortisone acetate into the intact 7,12dimethylbenz(a)...

background: cushing's disease is the most prevalent cause of endogenous adrenocorticotrophic hormone hypersecretion. the aim of this study was to document the current clinical practice pattern in the management of cushing's disease by iranian endocrinologists to determine their opinions and compare them with the current clinical practice guidelines.    methods: an eight-item questionn...

The relative rates of protein (hormone) synthesis and secretion by the various cell types in the anterior hypophysis of the rat have been studied by means of autoradiography. Normal and adrenalectomized male rats were injected with tritiated glycine and their hypophyses removed and fixed at 20, 40, and 90 minutes and 15 hours after injection. Autoradiograms of the hypophysial sections were prep...

BACKGROUND AND OBJECTIVES Several studies have been reported on the problem of determining when laparoscopic adrenalectomy is indicated for solitary adrenal metastasis of malignant tumors. Our efforts at answering this question constitute the basis of this report. METHODS From June 2010 to June 2011, laparoscopic adrenalectomy was performed in 10 lung cancer patients with solitary adrenal met...

The liver arginase in the rat decreases following adrenalectomy (Fraenkel-Conrat, Simpson & Evans, 1943; Folley & Greenbaum, 1946; Kochakian & Vail, 1947), and in lactating rats the mammarygland arginase behaves similarly (Folley & Greenbaum, 1946). It is possible that the decline in lactation causedby adrenalectomy (see, e.g., Cowie& Folley, 1947 a) is connected with the decrease in mammary-gl...

The aim of the present study was to present the treatment observations of patients with adrenocorticotrophic hormone (ACTH)-independent macronodular adrenal hyperplasia (AIMAH) from a single medical center. A total of 23 patients with AIMAH were retrospectively reviewed according to the clinical features of the patient. Physical symptoms and biochemical evidence of Cushing's syndrome (CS) were ...

BACKGROUND Retroperitoneal schwannomas are very rare and are usually found incidentally. CASES REPORT Two rare cases of retroperitoneal schwannomas are reported. Both were incidentally found during US scans for non-specific epigastric pain and were initially diagnosed as non-secreting retroperitoneal tumors. The diagnosis was confirmed by CT scan. In both patients the tumors were resected. Th...