نتایج جستجو برای: retinol binding protein

تعداد نتایج: 1449573  

Journal: :Proceedings of the National Academy of Sciences 1983

Journal: :Biochemistry 1992
B C Locke J M MacInnis S Qian J I Gordon E Li G R Fleming N C Yang

Rat intestinal cellular retinol binding protein II (CRBP II) is an abundant 134-residue protein that binds all-trans-retinol which contains 4 tryptophans in positions 9, 89, 107, and 110. Our ability to express CRBP II in Escherichia coli and to construct individual tryptophan substitution mutants by site-directed mutagenesis has provided a useful model system for studying the fluorescence of a...

Journal: :The Biochemical journal 2001
A Prior J T Jones V C Blok J Beauchamp L McDermott A Cooper M W Kennedy

Parasitic nematodes produce at least two structurally novel classes of small helix-rich retinol- and fatty-acid-binding proteins that have no counterparts in their plant or animal hosts and thus represent potential targets for new nematicides. Here we describe a protein (Gp-FAR-1) from the plant-parasitic nematode Globodera pallida, which is a member of the nematode-specific fatty-acid- and ret...

Journal: :Cell 2015
Christopher M. Chou Christine Nelson Susan A. Tarlé Jonathan T. Pribila Tanya Bardakjian Sean Woods Adele Schneider Tom Glaser

Gestational vitamin A (retinol) deficiency poses a risk for ocular birth defects and blindness. We identified missense mutations in RBP4, encoding serum retinol binding protein, in three families with eye malformations of differing severity, including bilateral anophthalmia. The mutant phenotypes exhibit dominant inheritance, but incomplete penetrance. Maternal transmission significantly increa...

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