نتایج جستجو برای: response modification factor

تعداد نتایج: 1821336  

Journal: :Biopolymers 2013
Lili K Doerfel Marina V Rodnina

The elongation phase of translation is promoted by three universal elongation factors, EF-Tu, EF-Ts, and EF-G in bacteria and their homologs in archaea and eukaryotes. Recent findings demonstrate that the translation of a subset of mRNAs requires a fourth elongation factor, EF-P in bacteria or the homologs factors a/eIF5A in other kingdoms of life. EF-P prevents the ribosome from stalling durin...

2017
Natasha Vafadar-Isfahani Christina Parr Lara E McMillan Juliane Sanner Zhao Yeo Stephen Saddington Oliver Peacock Hazel A Cruickshanks Richard R Meehan Jonathan N Lund Cristina Tufarelli

Hypomethylation of LINE-1 repeats in cancer has been proposed as the main mechanism behind their activation; this assumption, however, was based on findings from early studies that were biased toward young and transpositionally active elements. Here, we investigate the relationship between methylation of 2 intergenic, transpositionally inactive LINE-1 elements and expression of the LINE-1 chime...

A. Asghari, B. Mirtamizdoust M. Ghaedi M. Hemati M. Rajabi

In this study, ZnO nanoparticles were loaded on activated carbon prepared from almond shell (ZnO-NP-AC). Then, this novel material applied as an efficient adsorbent for the ultrasonic assisted simultaneous removal of Basic Blue 41(BB41) and Basic Red 46 (BR46) in binary solution.  The efficiency of proposed activated carbon was enhanced by acid treatment and subsequent modification by physical ...

R. Garcia, S.S. Athari,

Allergic asthma is the most common acute inflammatory airway disorder and their incidence population has exploded in the last years, being estimated that over 300 million people worldwide have the condition. Here, we present a brief overview of relationship of allergic asthma with diet and food intake. Several studies have shown that most asthma cases are due to an allergic immune response to e...

Journal: :Molecular cell 2005
Chuan He Jean-Christophe Hus Li Jing Sun Pei Zhou Derek P G Norman Volker Dötsch Hua Wei John D Gross William S Lane Gerhard Wagner Gregory L Verdine

The transcriptional activity of many sequence-specific DNA binding proteins is directly regulated by posttranslational covalent modification. Although this form of regulation was first described nearly two decades ago, it remains poorly understood at a mechanistic level. The prototype for a transcription factor controlled by posttranslational modification is E. coli Ada protein, a chemosensor t...

Journal: :Molecular cell 2004
Kerri A Mowen Brandon T Schurter John W Fathman Michael David Laurie H Glimcher

Posttranslational modification of proteins within T cell receptor signaling cascades allows T lymphocytes to rapidly initiate an appropriate immune response. Here we report a role for arginine methylation in regulating cytokine gene transcription in the T helper lymphocyte. Inhibition of arginine methylation impaired the expression of several cytokine genes, including the signature type 1 and t...

Journal: :The EMBO journal 2006
Yasunori Shintani Seiji Takashima Yoshihiro Asano Hisakazu Kato Yulin Liao Satoru Yamazaki Osamu Tsukamoto Osamu Seguchi Hiroyuki Yamamoto Tomi Fukushima Kazuyuki Sugahara Masafumi Kitakaze Masatsugu Hori

Neuropilin-1 (NRP1) is a co-receptor for vascular endothelial growth factor (VEGF) that enhances the angiogenic signals cooperatively with VEGFR2. VEGF signaling is essential for physiological and pathological angiogenesis through its effects on vascular endothelial cells (ECs) and smooth muscle cells (SMCs), but the mechanisms coordinating this response are not well understood. Here we show th...

Journal: :Dental materials journal 2012
Sonia Santander Clara Alcaine Jaber Lyahyai Maria Angeles Pérez Clementina Rodellar Manuel Doblaré Ignacio Ochoa

Interaction between cells and implant surface is crucial for clinical success. This interaction and the associated surface treatment are essential for achieving a fast osseointegration process. Several studies of different topographical or chemical surface modifications have been proposed previously in literature. The Biomimetic Advanced Surface (BAS) topography is a combination of a shot blast...

2017
Young-Hwa Kim Kyung Hyun Min Zhantong Wang Jihoon Kim Orit Jacobson Peng Huang Guizhi Zhu Yijing Liu Bryant Yung Gang Niu Xiaoyuan Chen

Evading the reticuloendothelial system (RES) remains a critical challenge in the development of efficient delivery and diagnostic systems for cancer. Sialic acid (N-acetylneuraminic acid, Neu5Ac) is recognized as a "self" marker by major serum protein complement factor H and shows reduced interaction with the innate immune system via sialic acid-binding immunoglobulin-like lectin (Siglec), whic...

A. Kaveh , V.R. Mahdavi,

Endurance Time Acceleration Functions are specially predesigned intensifying excitation functions that their amplitude increases with time. On the other hand, wavelet transform is a mathematical tool that indicates time variations of frequency in a signal. In this paper, an approach is presented for generating endurance time acceleration functions (ETAFs) whose response spectrum is compatible w...

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