This paper reports the effect of superficial liquid mass flow rate and bed void fraction on the pressure drop, dynamic liquid hold-up, mean liquid residence time and biofilm wetting, in a co-current down-flow xylene-removing trickle bed air biofilter (TBAB). The gas–liquid pressure drop increased with liquid mass flow rate and it also increased with diminishing bed void fraction, the effect bei...

Residence time distribution (RTD) study of solids in a three-phase pilot-scale bubble column photoreactor has been carried out in order to provide data for the development of an artificial neural network model usable for process optimisation. The experimental data indicated that the RTD of solids was a complex nonlinear function of gas and liquid velocities as well as the contacting pattern (co...

Infiltration percolation is used as a tertiary treatment in order to meet the WHO’s microbiological standards applying to unrestricted agricultural wastewater reuse. Faecal coliform removal, ∆fc, was investigated in laboratory columns and on a 565 m pilot plant. ∆fc observed in laboratory columns was shown to be closely related to water detention time distribution, DTD. The relationship between...

Recently, extensive studies have been carried out on micro chemical process technologies (Jensen, 2001; Fletcher et al., 2002). In particular, analysis of chemical reactions and transport phenomena in micro-space has been performed energetically. However, most microreactors are designed and fabricated by trial and error -there is no systematic procedure for developing microreactors. Therefore, ...

We consider the problem of stochastic averaging of a quantum two-state dynamics driven by non-Markovian, discrete noises of the continuous time random walk type (multistate renewal processes). The emphasis is put on the proper averaging over the stationary noise realizations corresponding, e.g., to a stationary environment. A two-state non-Markovian process with an arbitrary non-exponential dis...

Soil and epikarst play an important role in the hydrological cycle in karst regions. This paper focuses on investigating the seasonal recharge and mean residence time (MRT) of soil water and epikarst water in a small karst catchment of southwest China. The deuterium contents in precipitation, creek, soil baseflow (direct recharge of the saturated soil water to the stream), epikarst spring, and ...

The bioequivalence of three chemically equivalent paracetamol generic Mexican products (500 mg tablets) was evaluated in 12 healthy volunteers using the American innovator product (Tylenol, McNeil, Fort Washington, PA), as the reference. Single oral doses of each product were administered at 1-week intervals using a 4 x 4 Latin square design balanced for the first residual effect. The total amo...

In a study of the timing mechanism of the chaperonin nanomachine we show that the hemicycle time (HCT) is determined by the mean residence time (MRT) of GroES on the cis ring of GroEL. In turn, this is governed by allosteric interactions within the trans ring of GroEL. Ligands that enhance the R (relaxed) state (residual ADP, the product of the previous hemicycle, and K(+)) extend the MRT and t...

In this study, an open, double-blind, randomized, two-period, two-group crossover design was conducted in 14 healthy volunteers to study the bioequivalence of a fixed-dose generic product. After administration of test or reference products to each volunteer, both active ingredients were determined simultaneously in plasma samples using a developed and validated HPLC-UV method, and pharmacokinet...

– The distribution of bursting lengths of neuron spikes, in a two-component integrate-and-fire model, is investigated. The stochastic process underlying this model corresponds to a generalisation of the Brownian motion underlying Levy’s arcsine law of residence times. The generalisation involves the inclusion of a quadratic potential of strength γ and γ = 0 corresponds to Levy’s original proble...