BACKGROUND This study examined medical resource utilisation patterns in the United Kingdom (UK) prior to and following Alzheimer's disease (AD) diagnosis. METHODS A patient cohort aged 65 years and older with newly diagnosed AD between January 2008 and December 2010 was identified through the UK's Clinical Practice Research Datalink (CPRD). Patients with a continuous record in the CPRD (forme...

The NAIRU is the rate of unemployment consistent with stable inflation... An important challenge in setting economic policy is to identify the rate of capacity utilisation that is sustainable, in the sense that it is associated with reasonably stable inflation. There are different ways of measuring capacity utilisation. Looking at perhaps the most common measure, unemployment, this idea of sust...

Current conceptualisations of information systems strategy (ISS) in knowledge-based small and medium enterprises (KSMEs) suggest the utilisation of a core competencies approach. This research explores the current nature of ISS in twelve Australian SMEs in one of the most knowledge intensive industries, the biotechnology industry. An emergent model is presented and evaluated against existing lit...

Recycling of by-products of the steelmaking process in electric arc (EAF) furnaces is an important activity from the perspective of environmental protection as well as the steelmaking industry itself. This article is a discussion concerning the selected research results in terms of utilisation of steelmaking dusts containing 4 12 % of zinc in manufacture of cement bricks, ceramic construction m...

The selection and utilisation of metabolic substrates during endurance exercise are regulated by a complex array of effectors. These factors include, but are not limited to, endurance training and cardiorespiratory fitness, exercise intensity and duration, muscle morphology and histology, hormonal factors and diet. Although the effects of these factors on substrate utilisation patterns are well...

The timely article by Verdoux & Begaud ́ hopefully begins to redress the imbalance between randomised controlled trials and other ways of evaluating drug treatments. I would like to present further evidence for the ‘gap between guidelines and utilisation . . . for psychotropic medications’ (Verdoux & Begaud, 2004). ́ Using the Drug Report of the German Public Health Insurance (Schwabe & Pfaffrath...

The major catabolic enzyme for serotonin, monoamine oxidase (MAO), is present in the endothelium of cerebral vessels. We report the effects of the intracarotid administration of serotonin on local cerebral glucose utilisation in rats following MAO inhibition with the drug clorgyline. It was found that saline, clorgyline, or serotonin alone produced no significant changes in glucose utilisation....

In this paper, we re-analyse the Rate Monotonic Scheduler. Traditionally, the schedulability condition was obtained from the greatest lower bound of utilisation factors over all the task sets that (are schedulable and) fully utilise the processor. We argue that full utilisation is not very appropriate for this purpose. We reestablish Liu and Layland’s classic schedulability theorem by finding t...

The timely article by Verdoux & Begaud ́ hopefully begins to redress the imbalance between randomised controlled trials and other ways of evaluating drug treatments. I would like to present further evidence for the ‘gap between guidelines and utilisation . . . for psychotropic medications’ (Verdoux & Begaud, 2004). ́ Using the Drug Report of the German Public Health Insurance (Schwabe & Pfaffrath...

OBJECTIVE To investigate the incidence, anatomical correlates, and clinical features of imitation and utilisation behaviour, which are thought by Lhermitte and coworkers to represent a reliable and frequent index of frontal lobe disease. METHODS 78 patients with hemispheric local lesions were tested in two separate sessions, in which their reactions to a series of gestures performed by the ex...