Transforming growth factor-beta (TGFbeta) homologues form a diverse superfamily that arose early in animal evolution and control cellular function through membrane-spanning, conserved serine-threonine kinases (RII and RI receptors). Activin and inhibin are related dimers within the TGFbeta superfamily that share a common beta-subunit. The evolution of the inhibin alpha-subunit created the only ...

This study reviews the roles of steroid receptors, mainly oestrogen receptor alpha (ERα) and progesterone receptor (PR) in pig uterine tissues with an emphasis on various stages of the oestrous cycle comparing to the time of early pregnancy. In addition, the secretory and proliferative activities under the influence of steroid hormones and their specific receptors were also documented. Some dif...

In this study, a methodological approach based on the model of differential equations system to determine impact functions public administration regional development in context digital transformation is proposed. As involves changes management models systems at different levels order improve their efficiency, also applies development. Based approach, social, reproductive and mobilizing state we...

Although ovarian estrogen, estradiol-17beta, is a key modulator of normal reproductive functions, natural and synthetic compounds with estrogen-like activities can further influence reproductive functions. Plant-derived phytoestrogens specifically have received much attention because of associated health benefits. However, a comprehensive understanding of the beneficial and/or detrimental impac...

Reproductive functions may be altered by the exposure to a multitude of endogenous and exogenous agents, drug or environmental pollutants, which are known to affect gene transcription through the peroxisome proliferator-activated receptors (PPARs) activation. PPARs act as ligand activated transcription factors and regulate metabolic processes such as lipid and glucose metabolism, energy homeost...

Prolactin (PRL) has one of the broadest ranges of functions of any vertebrate hormone, and plays a critical role in regulating aspects of reproduction in widely divergent lineages. However, while PRL structure, mode of action and functions have been well-characterised in mammals, studies of other vertebrate lineages remain incomplete. As the most diverse group of vertebrates, fish offer a parti...

Abstract Background The global prevalence of obesity has soared to a concerning height in the past few decades. Interestingly, decline semen quality is parallel occurrence that urges researchers evaluate if among most essential causatives male infertility or subfertility. Main body Obesity may alter synchronized working reproductive-endocrine milieu, mainly hypothalamic-pituitary-gonadal (HPG) ...

quantitative ultrasound (qus) is a noninvasive, inexpensive and portable method for bone densitometry. it may measure some other parameters in addition to bmd, like elasticity and micro architecture. this study designed to determine the relation between reproductive factors and calcaneus qus parameters in normal women of tehran. bmd of heel in 151 normal women, 20-72y/o (participator of iranian...