OVER the past 250 years, many accounts of status epilepticus have been published, but its true frequency is difficult to judge. Status epilepticus has been recognized as a clinical entity since 1824 when Calmeil first described patients who had repeated or prolonged uninterrupted epileptic seizures. It has been estimated that about 5% of all epileptic patients at some time in their lives experi...

delayed neuronal death after seizure attack may be mediated by the induction of apoptosis-pathway. caspase-3, a mammalian cysteine protease, promotes apoptosis after some neurological disorders. neuron regeneration peptides (nrps) are small synthetic peptides that stimulate neural proliferation, migration, and differentiation with no apparent toxicity and high target specificity in cns. in the ...

background: diagnosis of psychogenic non-epileptic seizures (pnes) particularly in patients with epilepsy poses a challenge to physicians to care. this study is aimed at determining the frequency of depression and anxiety among iranian patients with pnes. materials and methods: sixty patients with pnes and one hundred age-and-sex matching healthy controls were enrolled in this study from januar...

Repeated electrical stimulation of certain brain areas in the rat can decrease thresholds for epileptiform after-discharge (AD) in those areas (Racine 1972). Motor seizures, which cannot initially be evoked by electrical stimulation of subcortical nuclei in the rat, can also be developed by daily electrical stimulation via implanted electrodes (Goddard et al. 1969). Goddard et al., however, rec...

how to cite this article : salehiomran mr, hoseini sm, ghabeli juibary a. intermittent diazepam versus continuous phenobarbital to prevent recurrence of febrile seizures: a randomized controlled trial. iran j child neurol. winter 2016;10(1):21-24. abstract objective febrile seizure is the most common neurologic problem in children between 3 months to 5 years old. two to five percent of children...

how to cite this article: sadeghzadeh m, khoshnevis p, mahboubi e. iron status and febrile seizure- a case control study in children less than 3 years. iran j child neurol autumn 2012; 6(4):27-31. abstract objective: febrile seizure is one of the most common neurological conditions of childhood. several theories, such as iron deficiency anemia have been proposed as the pathogenesis of this cond...

Regarding the therapeutic properties of Nigella sativa (NS), the effects of the plant hydro - alcoholic extract on learning, memory and brain tissues oxidative damage were investigated in penthylenetetrazole (PTZ) - induced repeated seizures. There were 4 experimental groups including: 1- control group; received saline, 2- PTZ group ; received saline and PTZ (50 mg/Kg, i.p) , 3-PTZ- NS 200 and ...

Spontaneous antenatal hypoxia is associated with high risk of adverse outcomes, however, there is little information on neural adaptation to labor-like insults. Chronically instrumented near-term sheep fetuses (125 ± 3 days, mean ± SEM) with baseline PaO2 < 17 mmHg (hypoxic group: n = 8) or > 17 mmHg (normoxic group: n = 8) received 1-minute umbilical cord occlusions repeated every 5 minutes fo...

OBJECTIVES the aim of our study was to evaluate the activity of superoxide dismutase (SOD) and the levels of glutathione (GSH), malondialdehyde (MDA), and nitric oxide (NO) in liver and kidney tissues in a rat model of convulsive seizure induced by single and repeated doses of pentylenetetrazole (PTZ) and sound stimulation with key ringing. MATERIALS AND METHODS male Wistar adult rats (n=48),...