BACKGROUND We evaluated the concept of whether liver failure patients with a superimposed kidney injury receiving a simultaneous liver and kidney transplant (SLKT) have similar outcomes compared to patients with liver failure without a kidney injury receiving a liver transplantation (LT) alone. METHODS Using data from the United Network of Organ Sharing (UNOS) database, patients were divided ...

Blastocystis hominis is an intestinal protozoan that is emerging as an important cause of diarrhea in the immunosuppressed population. We report two cases of diarrhea caused by this organism in renal transplant recipients. The infection was diagnosed promptly by careful stool examination and treated successfully with metronidazole. These case report highlights the fact that unusual parasites li...

Despite progress in preventing and controlling infectious complications of renal transplantation, posttransplantation viral infections remain a significant threat to patients’ health. Optimizing outcomes after renal transplantation depends on effective management of posttransplant infectious complications. This paper discusses manifestations, prevention, diagnosis, and treatment of common viral...

In an effort to replace HPLC for whole-blood determination of cyclosporine (CsA), we compared HPLC with radioimmunoassay (RIA; INCSTAR, Cyclo-Trac SP assay), fluorescence polarization immunoassay (FPIA; Abbott TDx), and in-house modified enzyme-multiplied immunoassay technique (EMIT; Syva Co.). For blood samples from 200 various transplant recipients, RIA = 1.262 (HPLC) - 8.16, r = 0.983; FPIA ...

Cardiovascular disease remains the leading cause of death in renal transplant recipients, but the underlying causative mechanisms for this important problem remain elusive. Recent work has indicated that qualitative alterations of HDL affect its functional and compositional properties in ESRD. Here, we systematically analyzed HDL from stable renal transplant recipients, according to graft funct...

BACKGROUND/AIMS Individuals who reach end-stage kidney disease (CKD5) have a high risk of vascular events that persists even after renal transplantation. This study compared the prevalence and severity of microvascular disease in transplant recipients and patients with CKD5. METHODS Individuals with a renal transplant or CKD5 were recruited consecutively from renal clinics, and underwent bila...

BACKGROUND BK virus nephropathy (BKVN) is one of the complications of renal transplantation that causes graft loss in renal transplant recipients. OBJECTIVE To determine the incidence of BKVN after renal transplantation in Hasheminejad Hospital, Tehran, Iran. METHODS In this analytical cross-sectional study, we evaluated 31 consecutive kidney transplant recipients (21 men and 10 women) for ...

BACKGROUND Immunosuppressive therapy, which is necessary to avoid graft rejection in renal transplant recipients, presents an increased risk of several pathologies, namely infectious and neoplastic. OBJECTIVES To identify the most frequent skin diseases and their clinical and demographical risk factors within a population of renal transplant recipients. METHODS A retrospective study of rena...

background the human leukocyte antigen (hla) system is widely used as a strategy in the search for the etiology of renal function impairment. objectives this study was carried out to detect the most common hla alleles’ distribution in kidney transplant in both donors and recipients, and clarify the association between hla alleles and renal dysfunction immediately after transplantation. patients...

BACKGROUND Graft-site candidiasis rarely develops in solid organ transplant recipients; however, severe life-threatening complications can occur. We report the course of 3 solid organ transplant recipients developing graft-site candidiasis. CASE REPORT All grafts, consisting of 2 kidneys and 1 liver, were procured from a single donor. Patient data were collected from our database. Candida albic...