microparticles offer various significant advantages as drug delivery systems, including: (i) an effective protection of the encapsulated active agent against (e.g. enzymatic) degradation, (ii) the possibility to accurately control the release rate of the incorporated drug over periods of hours to months, (iii) an easy administration (compared to alternative parenteral controlled release dosage ...

extended release formulation of alfuzosin, an a-antagonist used for prostatic hypertrophy, is available in market. it is convenient for older patients to take only one tablet a day. marketed alfuzosin formulation is three layered geomatrix tablet that requires special facilities, high cost, more time and complex operation than normal direct compression formulation. therefore, a less complicated...

abstract mineral weathering is a major source of most essential nutrients including potassium. it is well known that potassium plays an important role in improving the quality of agricultural products and micaceous minerals, as the major source of potassium, are abundant in iranian soils. no information is available on the role of micaceous minerals in supplying k to barley as the second major ...

abstract heated micaceous minerals under different commercial brand names (including vermiculite) are used as culture medium in greenhouses. heating minerals affects the release of elements, such as potassium, by changing their structure. the present study, investigates the ability of alfalfa, as one of the most important fodder around the world, to take up the non-exchangeable and structural p...

The main aim of this study was preparation and evaluation of extended - release system ofthe anxiolytic substance. Alprazolam is a short-acting benzodiazepine with general propertiessimilar to those of diazepam. Our studies focused on development of extended drug deliverysystem based on Hydroxy Propyl Methyl Cellulose (HPMC 4000cps) as retard agent andPolyvinylpyrrolidone (PVP k30) as binder us...

The present study is aimed at the overall improvement in the efficacy, reduced toxicity and enhancement of therapeutic index of cisplatin. Nanocapsules of cisplatin containing ethylcellulose have been prepared using solvent evaporation technique under ambient conditions. The prepared nanocapsules were used for controlled drug release of anticancer agents with gold and iron oxide nanoparticles. ...

Introduction: Glass ionomer cement (GIC) is a restorative material used in pediatric dentistry, which attaches to dental hard tissues and has cariostatic properties due to the ability for fluoride release. The present study aimed to assess the fluoride release and uptake capacity of two GICs in the presence of various fluoride sources. Methods: This in-vitro study was conducted on 120 disks com...