During the 2015 State of the Union address, President Obama unveiled plans for a $215 million Precision Medicine Initiative. The details of this plan were laid out by past and present directors of the National Institutes of Health, Harold Varmus and Francis Collins, in a commentary in the New England Journal of Medicine. While the announcement stood as a public statement of support for funding,...

N-Acetylcysteine is a thiol antioxidant with expanding clinical importance. A sensitive, rapid method for determining reduced N-acetylcysteine (NAC) concentration in biological samples has been developed which uses a modified reversed-phase high-performance liquid chromatography (HPLC) technique in conjunction with the derivatizing agent N-(1-pyrenyl)maleimide (NPM). The NAC-NPM adduct was anal...

Our study describes the procedure development and validation of the GC-FID method for the determination of ethanol content in marjoram ointment. At the validation procedure linearity ranged from 1 x 10(-4)% to 1 x 10(-1)%, limit of detection was 5 x 10(-5)%, relative standard deviation for precision RSD = 1.07%, relative standard deviation for intermediate precision RSD = 1.43% and good recover...

Two prior approaches to size processing are discussed in this paper. The first approach is based on measurements of mental size transformations, the second on measurements of thresholds for size and separation. We first analyze these prior approaches and point out differences among prior models and similarities among prior results. This analysis led to new psychophysical experiments that tested...

one method of seed placement into the soil as regards no-till system is the use of punch planting by which one can plant through a considerable depth of surface residue. the study was conducted using a 2?3 split-plot experimental design of three replications. the factors considered were two types of plantes (conventional planter vs. hinging pneumatic punch planter) and three levels of wheat res...

the emerging concept of personalized medicine or precision medicine has recently become more popular both among the health-care providers and patients. the focus of personalized medicine is to target prevention and treatment strategies based on patients’ variability in genotype, environment and lifestyle. since precision medicine will make the clinical guidelines much more conditional and branc...

Current theories of environmental cognition typically differentiate between an online, transient, and dynamic system of spatial representation and an offline and enduring system of memory representation. Here the authors present additional evidence for such 2-system theories in the context of the disorientation paradigm introduced by R. F. Wang and E. S. Spelke (2000). Several experiments repli...

Hexafluoroisopropanol (HFIP)-induced sodium dodecyl sulfate/dodecyltrimethylammonium bromide (SDS/DTAB) catanionic surfactant coacervate extraction method coupled with high performance liquid chromatography (HPLC) was used to detect the migration of phthalates from disposable tablewares to drinking water. The concentration factors are larger than 82 and extraction recoveries over 53% for water ...