Background: Recently, rituximab has been successfully used for the treatment of pemphigus family, the main subtype of which is pemphigus vulgaris (PV). The aim of this study was to determine the efficacy and safety of rituximab in refractory PV. Methods: In an observational study extending from November 2014 to February 2016, 30 patients with refractory PV were treated with rituximab. Response ...

in order to avoid using cytotoxic drugs and to minimize prednisolone side effects in frequent relapsing or steroid-dependent idiopathic nephrotic syndrome, 35 patients, 3 to 15 (mean= 8.1) years of age, were studied. while in remission for at least 6 weeks, the dose of prednisolone was reduced to 0.1-0.37 (mean= 0.23) mg/kg/day as a single dose for 12 to 72 (mean= 27.6) months. it was followed ...

background: the aim was to evaluate the relapse risk of vivax malaria in patients who received radical treatment in hormozgan province, a malarious area located on southeast of iran. methods: a total of 95 symptomatic vivax malaria infected patients were enrolled in urban health centers of bandar - abbas, minab, bandar-jask and bashagard districts of hormozgan province, southeast of iran from j...

background: one of the major challenges in current methadone maintenance treatment retention rates in the treatment and prevention of relapse addiction. the aim of this study was determine the factors influencing relapse based on health belief model. methods: a cross-sectional study was conducted among 384 patients on methadone maintenance treatment referred to addiction clinic in hamadan, whic...

conclusions our results showed that many personal, familial, and social factors play a role in addiction relapse. the high prevalence of return to addiction necessitates further strategies for the more optimal control of these factors. patients and methods in this descriptive study, 146 addicts referring to addiction treatment centers in the iranian city of ahvaz were selected via purposive and...

OBJECTIVE Schizophrenia is a mental disorder and characterized by abnormal social behavior and failure to recognize what is real. The current study was to explore the long-term effects of cognitive rehabilitation training on schizophrenia. METHODS Eighty six cases of hospitalized patients with schizophrenia were randomly divided into study group and control group. The relapse and employment (...

PURPOSE To evaluate the clinical outcome of a cohort of localized prostate cancer patients treated with 125-I permanent brachytherapy at the São José Hospital--CHLC, Lisbon. MATERIALS AND METHODS A retrospective analysis was carried out on 429 patients with low and intermediate-risk of prostate adenocarcinoma, according to the recommendations of the EORTC, who underwent 125I brachytherapies i...

BACKGROUND This study aimed to define factors associated with relapse among responders to pegylated interferon (PEG-IFN) plus ribavirin (RBV) therapy in chronic hepatitis C. METHODS A cohort of genotype 1b chronic hepatitis C patients treated with PEG-IFN plus RBV and who had an undetectable HCV RNA by week 12 (n=951) were randomly assigned to model derivation (n=636) or internal validation (...