This paper addresses how to assess the performance of refractivity-from-clutter (RFC) techniques in different regions of the world with varying duct strengths and statistics. The performance of evaporation duct estimation is investigated in littoral zones such as the North Sea, Wallops Island, Coast of California, Mediterranean, Persian Gulf, and Coast of Brazil. The effects of the radar freque...

In the present study quantitative structure activity relationship studies were performed on a series of N-{(1H-Benzo[d] Imidazol-1-yl) (Phenyl) Methylene} Benzenamine analogues as antifungal activity using Chem Office ultra 8.0.3. Multiple linear regression analysis was performed to derive quantitative structure activity relationship models which were further evaluated internally as well as ext...

Assessments of refractivity in a Fabry–Perot (FP) cavity by refractometry often encompass step which the penetration depth light into mirrors is estimated to correct for fraction length no gas can penetrate. However, as it currently carried out, this procedure not always coherently performed. Here, we discuss common pitfall that be reason and provide recipe on how perform FP-cavity-based withou...

Scintillations of a Ku-band satellite signal are observed in association with rain attenuation at Kolkata, India. The wavelet analysis of signal fluctuations, due to simultaneous occurrence of scintillations and attenuation, reveals the relative impact of different scales of refractivity structures on the signal at different instants of time. A positive relationship exists between the peaks in ...

A method is described for measuring the density distribution in an inhomogeneous medium. This method is based upon the classical Schlieren technique, known as Background Oriented Schlieren (BOS) method. The method measures the density dependence of the refractivity through the detection of the deflecting angle of a number of light beams passing through the space to be measured. The results of s...

The β₃ adrenergic receptor is raising as an important drug target for the treatment of pathologies such as diabetes, obesity, depression, and cardiac diseases among others. Several attempts to obtain selective and high affinity ligands have been made. Currently, Mirabegron is the only available drug on the market that targets this receptor approved for the treatment of overactive bladder. Howev...

We present a new atom type classification system for use in atom-based calculation of partition coefficient (log P) and molar refractivity (MR) designed in part to address published concerns of previous atomic methods. The 68 atomic contributions to log P have been determined by fitting an extensive training set of 9920 molecules, with r2 ) 0.918 and σ ) 0.677. A separate set of 3412 molecules ...

The pathogenesis of Alzheimer’s disease (AD) putatively involves a compromised blood-brain barrier (BBB). In particular, the importance of brain-to-blood transport of brain-derived metabolites across the BBB has gained increasing attention as a potential mechanism in the pathogenesis of neurodegenerative disorders such as AD, which is characterized by the aberrant polymerization and accumulatio...

The atmospheric range error in an electromagnetic signal arriving vertically at the earth is measured by the height integral of the refractivity N through the atmosphere. (N = 10^ (n-1) where n is the index of refraction.) N in the non-ionized atmosphere is the sum of "dry" and "wet" components, which are considered separately. Only the dry part is important at optical wavelengths,and the prese...

It is well known fact that the strengths of drug interactions with grapefruit juice (GFJ) differ greatly depending on the 1,4-dihydropyridine calcium channel antagonist (DHP) used. However, there are no available data on the relationship between interactions with GFJ and its physicochemical attributes. Therefore we endeavored to study the correlation between calculated logP values, indicating l...