نتایج جستجو برای: recurrent vulvovaginal candidiasis rvvc

تعداد نتایج: 137328  

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2015
Christina A Muzny Jane R Schwebke

Biofilms are microbial communities of surface-attached cells embedded in a self-produced extracellular matrix. They are of major medical significance because they decrease susceptibility to antimicrobial agents and enhance the spread of antimicrobial resistance. Biofilm-associated bacterial and fungal microorganisms have increasingly been recognized to play a role in multiple infectious disease...

Journal: :Clinical and vaccine immunology : CVI 2006
Jan Kosonen Arto Rantala Colin H Little Päivi Lintu Pirjo-Riitta Harjamäki George M Georgiou Robert E Cone Johannes Savolainen

In addition to cytokines, CD4+ T cells have been found to secrete soluble, T-cell-derived antigen binding molecules (TABMs). These antigen-specific immunoproteins are thought to have immunoregulatory properties in the suppression of cell-mediated immunity (CMI) because they often associate with interleukin-10 (IL-10) and transforming growth factor beta. Decreased CMI causes susceptibility to in...

Journal: :Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia 2000
A Helfgott N Eriksen C M Bundrick R Lorimor B Van Eckhout

OBJECTIVE This study was undertaken to compare the frequencies of vaginal infections among human immunodeficiency virus-infected women with those among human immunodeficiency virus-seronegative women. STUDY DESIGN Human immunodeficiency virus-seropositive women attending a comprehensive care center for human immunodeficiency virus disease at the outpatient department of an inner-city hospital...

Journal: :JPMA. The Journal of the Pakistan Medical Association 2012
Shaheen Akhtar Sadia Masood Saadia Tabassum Dilawar Abbas Rizvi

OBJECTIVE To compare the efficacy of fluconazole 150mg single dose and itraconazole 200mg twice for one day in the treatment of acute vulvovaginal candidiasis. METHODS The study was carried out at the Department of Dermatology, PNS Shifa Hospital, Karachi, from March, 2008 to February 2009 and comprised 60 women with clinical and mycological diagnosis of vaginal candidiasis. Diagnosis was bas...

2013
Sanne P Smeekens Frank L van de Veerdonk Bart Jan Kullberg Mihai G Netea

Candida spp. are medically important fungi causing severe mucosal and life-threatening invasive infections, especially in immunocompromised hosts. However, not all individuals at risk develop Candida infections, and it is believed that genetic variation plays an important role in host susceptibility. On the one hand, severe fungal infections are associated with monogenic primary immunodeficienc...

Journal: :Antimicrobial agents and chemotherapy 2015
Kaat De Cremer Ellen Lanckacker Tanne L Cools Marijke Bax Katrijn De Brucker Paul Cos Bruno P A Cammue Karin Thevissen

Mucosal biofilm-related fungal infections are very common, and the incidence of recurrent oral and vulvovaginal candidiasis is significant. As resistance to azoles (the preferred treatment) is occurring, we aimed at identifying compounds that increase the activity of miconazole against Candida albicans biofilms. We screened 1,600 compounds of a drug-repositioning library in combination with a s...

Journal: :The New England journal of medicine 2009
Bart Ferwerda Gerben Ferwerda Theo S Plantinga Janet A Willment Annemiek B van Spriel Hanka Venselaar Clara C Elbers Melissa D Johnson Alessandra Cambi Cristal Huysamen Liesbeth Jacobs Trees Jansen Karlijn Verheijen Laury Masthoff Servaas A Morré Gert Vriend David L Williams John R Perfect Leo A B Joosten Cisca Wijmenga Jos W M van der Meer Gosse J Adema Bart Jan Kullberg Gordon D Brown Mihai G Netea

Mucocutaneous fungal infections are typically found in patients who have no known immune defects. We describe a family in which four women who were affected by either recurrent vulvovaginal candidiasis or onychomycosis had the early-stop-codon mutation Tyr238X in the beta-glucan receptor dectin-1. The mutated form of dectin-1 was poorly expressed, did not mediate beta-glucan binding, and led to...

2013
Sachin C Deorukhkar Santosh Saini

Vulvovaginal candidiasis (VVC) is the most common manifestation of genital candidiasis (Achkar and Bettina 2010). It is defined as signs and symptoms of inflammation of the vulva and vagina in the presence of Candida spp (Achkar and Bettina, 2010). Clinical manifestations of VVC are pruritus, hyperemia, vaginal discomfort and leucorrhea, burning, soreness, dyspareunia and vaginal or vulvar eryt...

اصغری, محمد, رودبار محمدی, شهلا, رودباری, مریم, مرادی, راحله, مقدم بنائم, لیدا,

Background and Objective: Vulvovaginal Candidiasis is one of the most common vaginal infections which can be related to the use of IUD. Determination of candida species which lead to vulvovaginal candidiasis is very important for proper treatment. This study aims to assess the effect of IUD insertion on Candida fungal flora in cervicovaginal smears. Materials and Methods: This prospective longi...

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