نتایج جستجو برای: recurrent keratoconus

تعداد نتایج: 131129  

Journal: :Survey of ophthalmology 1998
Y S Rabinowitz

Keratoconus is a bilateral noninflammatory corneal ectasia with an incidence of approximately 1 per 2,000 in the general population. It has well-described clinical signs, but early forms of the disease may go undetected unless the anterior corneal topography is studied. Early disease is now best detected with videokeratography. Classic histopathologic features include stromal thinning, iron dep...

2016
Damien Gatinel

Keratoconus, a dystrophy of unknown origin, remains an ophthalmic enigma. The contrast between the presence of marked structural changes and deformation of the corneal wall and the relative absence of specific genetic and biomolecular findings continues to intrigue ophthalmologists. In Marfan syndrome, where genetic and molecular abnormalities are well identified, and similar changes in collage...

2015
Yanjun Hua Aleksander Stojanovic Tor Paaske Utheim Xiangjun Chen Sten Ræder Jinhai Huang Qinmei Wang

PURPOSE To determine the keratometric indices calculated based on parameters obtained by Fourier-domain optical coherence tomography (FD-OCT). METHODS The ratio of anterior corneal curvature to posterior corneal curvature (Ratio) and keratometric index (N) were calculated within central 3 mm zone with the RTVue FD-OCT (RTVue, Optovue, Inc.) in 186 untreated eyes, 60 post-LASIK/PRK eyes, and 3...

Journal: :Investigative ophthalmology & visual science 2013
Gulfidan Bitirgen Ahmet Ozkagnici Rayaz A Malik Refik Oltulu

PURPOSE To quantitatively analyze laser scanning in vivo confocal microscopy (IVCM) images of all corneal layers in contact lens-wearing and noncontact lens-wearing keratoconus patients. METHODS The study population included rigid gas permeable (RGP) contact lens-wearing keratoconus patients (group 1; N = 29), keratoconus patients who did not wear contact lenses (group 2; N = 30), and subject...

Journal: :Clinical & experimental optometry 2009
Paul Schoneveld Konrad Pesudovs Douglas J Coster

PURPOSE The aim was to identify optical quality metrics predictive of visual performance in eyes with keratoconus and penetrating keratoplasty (PK) for keratoconus. METHODS Fifty-four participants were recruited for this prospective, cross-sectional study. Data were collected from one eye of each participant: 26 keratoconus, 10 PK and 18 normal eyes: average age (mean +/- standard deviation) ...

Journal: :Journal of cataract and refractive surgery 2012
Emanuel S Rosen

Not too long ago, the options for treatment of keratoconus were limited to contact lens wear or penetrating keratoplasty. Times have changed, which is reflected in 4 articles in this issue that have some bearing on current investigation and treatment options. One hundred fifty years ago, Dr. John Nottingham provided the first detailed description of keratoconus, with further observations by his...

2011
Georgios Labiris Eleni Kaloghianni Stavrenia Koukoula Athanassios Zissimopoulos Vassilios P Kozobolis

INTRODUCTION Corneal collagen cross-linking is a rather new technique that uses riboflavin and ultraviolet A light for collagen fiber stabilization in keratoconus corneas. Other than reversible side effects, the preliminary results of corneal collagen cross-linking studies suggest that it is a rather safe technique. In this report, we demonstrate a case of corneal melting after corneal collagen...

2016
Deanne Lee Nicholas

Keratoconus, which is a degenerative collagen disorder, affects approximately 1 in 2000 individuals in the general population.1,2 This corneal ectasia usually presents at late puberty and is shown to progress for approximately 10–20 years.3 Keratoconus results in changes within the ordered distribution of collagen fibrils in the cornea, leading to loss of stiffness in the stromal structure.1 Th...

2017
Sara Ortiz-Toquero Raul Martin

K eratoconus early detection (screening) and diagnosis requires an in-deep corneal analysis with different techniques; slip lamp assessment, corneal topography and corneal tomography are the most commonly accepted to detect clinical signs and assess anterior and posterior corneal surface and global corneal pachymetry. However, keratoconus early detection and definitive diagnosis are two differe...

Journal: :Human molecular genetics 2015
Gabriel Cuellar-Partida Henriët Springelkamp Sionne E M Lucas Seyhan Yazar Alex W Hewitt Adriana I Iglesias Grant W Montgomery Nicholas G Martin Craig E Pennell Elisabeth M van Leeuwen Virginie J M Verhoeven Albert Hofman André G Uitterlinden Wishal D Ramdas Roger C W Wolfs Johannes R Vingerling Matthew A Brown Richard A Mills Jamie E Craig Caroline C W Klaver Cornelia M van Duijn Kathryn P Burdon Stuart MacGregor David A Mackey

Keratoconus is a degenerative eye condition which results from thinning of the cornea and causes vision distortion. Treatments such as ultraviolet (UV) cross-linking have proved effective for management of keratoconus when performed in early stages of the disease. The central corneal thickness (CCT) is a highly heritable endophenotype of keratoconus, and it is estimated that up to 95% of its ph...

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