STUDY DESIGN The serum levels of transforming growth factor-beta 1 (TGF-beta1), tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) and TIMP-2 were measured by enzyme-linked immunosorbent assay. PURPOSE To compare the serum levels of TGF-beta1, TIMP-1 and TIMP-2 between patients with lumbar spinal stenosis and disc herniation. OVERVIEW OF LITERATURE It has been reported that increased c...

BACKGROUND Percutaneous endoscopic lumbar discectomy is a common surgical treatment for lumbar disc herniation, and percutaneous endoscopic interlaminar lumbar discectomy (PEID) is commonly used for direct decompression of L5-S1. Like microdiscectomy, recurrence of herniation after endoscopic discectomy is an important problem. In this study, we aimed to decrease the recurrence after PEID using...

Clinical and Morphological Findings of Disc Herniation by use Different MRI Sequences Observers

BACKGROUND The usual surgical treatment of refractory sciatica caused by lumbar disc herniation, is open discectomy. Minimally invasive procedures, including percutaneous therapies under local anesthesia, are increasingly gaining attention. One of these treatments is Percutaneous Laser Disc Decompression (PLDD). This treatment can be carried out in an outpatient setting and swift recovery and r...

Introduction Many patients with extruded lumbar disc herniation require surgical intervention but some neurological symptoms of intervertebral disc herniation may often improve with conservative treatment. Patients usually try various treatment methods ranging from alternative treatments to surgery1,2. Recently, a new thermomechanical massage device has emerged, primarily in Asian countries, wi...

A 73-year-old man who presented with right lumbosciatic pain underwent a neurosurgical operation for a voluminous L2-L3 disc herniation, seen on conventional MRI images. No disc herniation was identified in the epidural space during the surgery. Just after the operation, the patient started to present pain in the left L3 territory and was not able to walk any more. A second MRI including three-...

What was once a simple lumbar disc herniation treated with laminotomy and partial discectomy, with typically excellent results (25, 46), has evolved into a surprisingly complex clinical problem with a dazzling array of therapeutic alternatives. Much of this, of course, is based on clinical studies emphasizing the heterogeneity of disc disorders. Advances in biomechanics research focusing on the...

STUDY DESIGN Retrospective review of imaging data from a clinical trial. OBJECTIVE To compare the interpretation of lumbar spine magnetic resonance imaging (MRIs) by clinical spine specialists and radiologists in patients with lumbar disc herniation. SUMMARY OF BACKGROUND DATA MRI is the imaging modality of choice for evaluation of the lumbar spine in patients with suspected lumbar disc her...

BACKGROUND Lumbar intervertebral disc herniation and spinal tumor are major pathologies that may cause back pain and radiculopathy. Neurological symptoms resulting from disc herniation and intradural spinal tumor together, however, are very rare. CASE PRESENTATION We report a case of lumbar disc herniation which coexists with intradural schwannoma at the same spinal level in a 67-year-old man...