Objective: Colon/rectum cancer often presents with intrapulmonary metastases. Surgical resection can be performed in a selected group of patients. In this study, the search for possible prognostic factors of patients with primary colon/rectum cancer and lung metastases was performed. Methods: Medical records of 110 patients operated on pulmonary metastases of primary colon/rectum cancer were re...

We investigated the association of colorectal cancer risk factors with different colorectal cancer subsites to assess etiological differences for cancers of the proximal colon, distal colon, and rectum. Included in this study were 869,725 men and 395,501 women who participated in a health examination provided by the Korean National Health System between 1996 and 1997. During up to 7 years of fo...

INTRODUCTION The colon and rectum are common sites of food-related cancer in developed countries. Recent studies strongly suggest that red meat intake is associated with colon cancer, whereas for rectal cancer such an association still needs to be proved. The aim of the study was to assess the role of total amount and frequency of red meat intake in colorectal carcinogenesis based on published ...

AIMS Recently, BRAF mutation testing has been introduced as a marker in differentiating Lynch syndrome from sporadic colorectal cancers or in predicting colorectal cancers with worse prognosis. Individuals with hereditary predisposition to cancer development are at an increased risk of developing multiple primary cancers. The purpose of this study is to identify mutation in the BRAF gene in mul...

The last decade is characterized by significant progress in the treatment of rectal cancer (reduction number relapses to 5–6 % with use prolonged radiation therapy) before surgery. greatest success has been achieved lower ampulla rectum, when it possible develop a complete clinical response tumor chemoradiotherapy. Nevertheless, requirement issues improve results upper and middle ampullar rectu...

PURPOSE To investigate the feasibility of progressive knowledge modeling for IMRT/VMAT treatment planning for multiple cancer types in the pelvic region. METHODS The treatment planning knowledge model quantifies correlations between patient anatomical features and the OAR dose sparing features. The model is trained with prior plans using a stepwise regression machine learning technique. The p...

Tumors of the rectum can be primary or metasta-tic, as observed with the other organs. Primary cancer of the rectum is not rare and accounts for one-third of all cases of colorectal cancer. Invasion of a cancer originating from other pelvic organs might also be seen. Beyond malignant diseases, rectal polyps are reported with a prevalence of 7-50% in the general population, especially in older p...