This study evaluated the consistency of manual and automated measurements of monodominant follicle diameter with different follicle size in infertile patients. Transvaginal two-dimensional (2D) ultrasound and SonoAVC (Sonography-based Automated Volume Calculation) were both performed in 226 infertile patients with monodominant follicle growth. 2D diameters were separately compared with SonoAVC-...

Background: Corifollitropin alfa (CFA) is a long-acting recombinant follicle-stimulating hormone (rFSH) used for controlled ovarian stimulation (COS). Several studies analyzing the clinical efficacy and safety of CFA compared to daily rFSH during COS have been carried out. The present study offers meta-analysis randomized trials (RCTs) on this topic. Methods: A computerized search published lit...

BACKGROUND The alpha particle emitter 211At is proposed for therapy of metastatic tumour disease. 211At is accumulated in the thyroid gland in a similar way as iodine. Dosimetric models of 211At in the thyroid are needed for radiation protection assessments for 1) patients receiving 211At-labelled pharmaceuticals where 211At may be released in vivo and 2) personnel working with 211At. Before cl...

Despite the significant advances in regenerative medicine, wound healing has remained a challenging clinical problem. Skin is the largest human organ with many vital functions; therefore, any damage to its normal structure should be treated as soon as possible. Easy access to skin stem cells has created a lot of excitement in therapeutic applications. “Cell therapy” is considered a novel method...

This manuscript reviews the present knowledge related to folliculogenesis in sheep.Folliculogenesis starts with formation of primordial follicles before birth, present as a pool containing a certain number of follicles. By the attainment of puberty, a group of follicles from that pool starts to grow, a process known as primordial follicle activation or recruitment. The number of growing primord...

background: the interaction between follicular cells and oocyte leads to a change in gene expression involved in oocyte maturation processes. objective: the purpose of this study was to quantify the expression of more common genes involved in follicular growth and oocyte developmental competence. materials and methods: in this experimental study, the expression of genes was evaluated with qrt-p...

We have developed a protocol using recombinant human follicle-stimulating hormone (rhFSH) to induce ovarian stimulation in the mouse to investigate its impact on preimplantation embryo development. Embryos were collected from adult female C57Bl/6 x CBA F1 mice treated with rhFSH (0, 2.5, 5.0, 10.0, or 20.0 IU) or 5 IU equine chorionic gonadotropin (eCG). Embryos were also recovered from nontrea...